Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes

Mark A. Espeland; Henry A. Glick; Alain Bertoni; Frederick L. Brancati; George A. Bray; Jeanne M. Clark; Jeffrey M. Curtis; Caitlin Egan; Mary Evans; John P. Foreyt; Siran Ghazarian; Edward W. Gregg; Helen P. Hazuda; James O. Hill; Don Hire; Edward S. Horton; Van S. Hubbard; John M. Jakicic; Robert W. Jeffery; Karen C. Johnson; Steven E. Kahn; Tina Killean; Abbas E. Kitabchi; William C. Knowler; Andrea Kriska; Cora E. Lewis; Marsha Miller; Maria G. Montez; Anne Murillo; David M. Nathan; Ebenezer Nyenwe; Jennifer Patricio; Anne L. Peters; Xavier Pi-Sunyer; Henry Pownall; J. Bruce Redmon; Julia Rushing; Donna H. Ryan; Monika Safford; Adam G. Tsai; Thomas A. Wadden; Rena R. Wing; Susan Z. Yanovski; Ping Zhang

doi:10.2337/dc14-0093

Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes

Mark A. Espeland, Henry A. Glick, Alain Bertoni, Frederick L. Brancati, George A. Bray, Jeanne M. Clark, Jeffrey M. Curtis, Caitlin Egan, Mary Evans, John P. Foreyt, Siran Ghazarian, Edward W. Gregg, Helen P. Hazuda, James O. Hill, Don Hire, Edward S. Horton, Van S. Hubbard, John M. Jakicic, Robert W. Jeffery, Karen C. JohnsonSteven E. Kahn, Tina Killean, Abbas E. Kitabchi, William C. Knowler, Andrea Kriska, Cora E. Lewis, Marsha Miller, Maria G. Montez, Anne Murillo, David M. Nathan, Ebenezer Nyenwe, Jennifer Patricio, Anne L. Peters, Xavier Pi-Sunyer, Henry Pownall, J. Bruce Redmon, Julia Rushing, Donna H. Ryan, Monika Safford, Adam G. Tsai, Thomas A. Wadden, Rena R. Wing, Susan Z. Yanovski, Ping Zhang

Research output: Contribution to journal › Article › peer-review

146 Scopus citations

Abstract

OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial. RESEARCH DESIGN AND METHODS A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years. RESULTS: ILI led to reductions in annual hospitalizations (11%, P = 0.004), hospital days (15%, P = 0.01), and number of medications (6%, P < 0.001), resulting in cost savings for hospitalization (10%, P = 0.04) and medication (7%, P < 0.001). ILI produced a mean relative per-person 10-year cost savings of $5,280 (95% CI 3,385-7,175); however, these were not evident among individuals with a history of cardiovascular disease. CONCLUSIONS: Compared with DSE over 10 years, ILI participants had fewer hospitalizations, fewer medications, and lower health-care costs.

Original language	English (US)
Pages (from-to)	2548-2556
Number of pages	9
Journal	Diabetes care
Volume	37
Issue number	9
DOIs	https://doi.org/10.2337/dc14-0093
State	Published - Sep 2014

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Advanced and Specialized Nursing

Access to Document

10.2337/dc14-0093

Cite this

Espeland, M. A., Glick, H. A., Bertoni, A., Brancati, F. L., Bray, G. A., Clark, J. M., Curtis, J. M., Egan, C., Evans, M., Foreyt, J. P., Ghazarian, S., Gregg, E. W., Hazuda, H. P., Hill, J. O., Hire, D., Horton, E. S., Hubbard, V. S., Jakicic, J. M., Jeffery, R. W., ... Zhang, P. (2014). Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes. Diabetes care, 37(9), 2548-2556. https://doi.org/10.2337/dc14-0093

Espeland, MA, Glick, HA, Bertoni, A, Brancati, FL, Bray, GA, Clark, JM, Curtis, JM, Egan, C, Evans, M, Foreyt, JP, Ghazarian, S, Gregg, EW, Hazuda, HP, Hill, JO, Hire, D, Horton, ES, Hubbard, VS, Jakicic, JM, Jeffery, RW, Johnson, KC, Kahn, SE, Killean, T, Kitabchi, AE, Knowler, WC, Kriska, A, Lewis, CE, Miller, M, Montez, MG, Murillo, A, Nathan, DM, Nyenwe, E, Patricio, J, Peters, AL, Pi-Sunyer, X, Pownall, H, Redmon, JB, Rushing, J, Ryan, DH, Safford, M, Tsai, AG, Wadden, TA, Wing, RR, Yanovski, SZ & Zhang, P 2014, 'Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes', Diabetes care, vol. 37, no. 9, pp. 2548-2556. https://doi.org/10.2337/dc14-0093

@article{06f3ea00f553433584349e7b537acf07,

title = "Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes",

abstract = "OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial. RESEARCH DESIGN AND METHODS A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years. RESULTS: ILI led to reductions in annual hospitalizations (11%, P = 0.004), hospital days (15%, P = 0.01), and number of medications (6%, P < 0.001), resulting in cost savings for hospitalization (10%, P = 0.04) and medication (7%, P < 0.001). ILI produced a mean relative per-person 10-year cost savings of $5,280 (95% CI 3,385-7,175); however, these were not evident among individuals with a history of cardiovascular disease. CONCLUSIONS: Compared with DSE over 10 years, ILI participants had fewer hospitalizations, fewer medications, and lower health-care costs.",

author = "Espeland, {Mark A.} and Glick, {Henry A.} and Alain Bertoni and Brancati, {Frederick L.} and Bray, {George A.} and Clark, {Jeanne M.} and Curtis, {Jeffrey M.} and Caitlin Egan and Mary Evans and Foreyt, {John P.} and Siran Ghazarian and Gregg, {Edward W.} and Hazuda, {Helen P.} and Hill, {James O.} and Don Hire and Horton, {Edward S.} and Hubbard, {Van S.} and Jakicic, {John M.} and Jeffery, {Robert W.} and Johnson, {Karen C.} and Kahn, {Steven E.} and Tina Killean and Kitabchi, {Abbas E.} and Knowler, {William C.} and Andrea Kriska and Lewis, {Cora E.} and Marsha Miller and Montez, {Maria G.} and Anne Murillo and Nathan, {David M.} and Ebenezer Nyenwe and Jennifer Patricio and Peters, {Anne L.} and Xavier Pi-Sunyer and Henry Pownall and Redmon, {J. Bruce} and Julia Rushing and Ryan, {Donna H.} and Monika Safford and Tsai, {Adam G.} and Wadden, {Thomas A.} and Wing, {Rena R.} and Yanovski, {Susan Z.} and Ping Zhang",

year = "2014",

month = sep,

doi = "10.2337/dc14-0093",

language = "English (US)",

volume = "37",

pages = "2548--2556",

journal = "Diabetes care",

issn = "0149-5992",

publisher = "American Diabetes Association Inc.",

number = "9",

}

TY - JOUR

T1 - Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes

T2 - The action for health in diabetes

AU - Espeland, Mark A.

AU - Glick, Henry A.

AU - Bertoni, Alain

AU - Brancati, Frederick L.

AU - Bray, George A.

AU - Clark, Jeanne M.

AU - Curtis, Jeffrey M.

AU - Egan, Caitlin

AU - Evans, Mary

AU - Foreyt, John P.

AU - Ghazarian, Siran

AU - Gregg, Edward W.

AU - Hazuda, Helen P.

AU - Hill, James O.

AU - Hire, Don

AU - Horton, Edward S.

AU - Hubbard, Van S.

AU - Jakicic, John M.

AU - Jeffery, Robert W.

AU - Johnson, Karen C.

AU - Kahn, Steven E.

AU - Killean, Tina

AU - Kitabchi, Abbas E.

AU - Knowler, William C.

AU - Kriska, Andrea

AU - Lewis, Cora E.

AU - Miller, Marsha

AU - Montez, Maria G.

AU - Murillo, Anne

AU - Nathan, David M.

AU - Nyenwe, Ebenezer

AU - Patricio, Jennifer

AU - Peters, Anne L.

AU - Pi-Sunyer, Xavier

AU - Pownall, Henry

AU - Redmon, J. Bruce

AU - Rushing, Julia

AU - Ryan, Donna H.

AU - Safford, Monika

AU - Tsai, Adam G.

AU - Wadden, Thomas A.

AU - Wing, Rena R.

AU - Yanovski, Susan Z.

AU - Zhang, Ping

PY - 2014/9

Y1 - 2014/9

N2 - OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial. RESEARCH DESIGN AND METHODS A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years. RESULTS: ILI led to reductions in annual hospitalizations (11%, P = 0.004), hospital days (15%, P = 0.01), and number of medications (6%, P < 0.001), resulting in cost savings for hospitalization (10%, P = 0.04) and medication (7%, P < 0.001). ILI produced a mean relative per-person 10-year cost savings of $5,280 (95% CI 3,385-7,175); however, these were not evident among individuals with a history of cardiovascular disease. CONCLUSIONS: Compared with DSE over 10 years, ILI participants had fewer hospitalizations, fewer medications, and lower health-care costs.

AB - OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and costs of health care within the Look AHEAD trial. RESEARCH DESIGN AND METHODS A total of 5,121 overweight or obese adults with type 2 diabetes were randomly assigned to an ILI that promoted weight loss or to a comparison condition of diabetes support and education (DSE). Use and costs of health-care services were recorded across an average of 10 years. RESULTS: ILI led to reductions in annual hospitalizations (11%, P = 0.004), hospital days (15%, P = 0.01), and number of medications (6%, P < 0.001), resulting in cost savings for hospitalization (10%, P = 0.04) and medication (7%, P < 0.001). ILI produced a mean relative per-person 10-year cost savings of $5,280 (95% CI 3,385-7,175); however, these were not evident among individuals with a history of cardiovascular disease. CONCLUSIONS: Compared with DSE over 10 years, ILI participants had fewer hospitalizations, fewer medications, and lower health-care costs.

UR - http://www.scopus.com/inward/record.url?scp=84906706277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906706277&partnerID=8YFLogxK

U2 - 10.2337/dc14-0093

DO - 10.2337/dc14-0093

M3 - Article

C2 - 25147253

AN - SCOPUS:84906706277

SN - 0149-5992

VL - 37

SP - 2548

EP - 2556

JO - Diabetes care

JF - Diabetes care

IS - 9

ER -

Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: The action for health in diabetes

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this