Immunohistochemical demonstration of multiple neurohormonal polypeptides in a case of pure testicular carcinoid

N. G. Ordonez; Alberto Ayala; N. Sneige; B. Mackay

doi:10.1093/ajcp/78.6.860

Immunohistochemical demonstration of multiple neurohormonal polypeptides in a case of pure testicular carcinoid

N. G. Ordonez, Alberto Ayala, N. Sneige, B. Mackay

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Abstract

A primary pure testicular carcinoid from a 48-year-old man was examined with antisera raised against various neurohormonal polypeptides. Histochemically, both argyrophil and argentaffin reactions were positive. The immunohistochemical finding of immunoreactive cells for 5-hydroxytryptamine (5-HT) (serotonin), substance P, and vasoactive intestinal polypeptide (VIP) demonstrated the multihormonal nature of this tumor.

Original language	English (US)
Pages (from-to)	860-864
Number of pages	5
Journal	American Journal of Clinical Pathology
Volume	78
Issue number	6
DOIs	https://doi.org/10.1093/ajcp/78.6.860
State	Published - Jan 1 1982

ASJC Scopus subject areas

Pathology and Forensic Medicine

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abstract = "A primary pure testicular carcinoid from a 48-year-old man was examined with antisera raised against various neurohormonal polypeptides. Histochemically, both argyrophil and argentaffin reactions were positive. The immunohistochemical finding of immunoreactive cells for 5-hydroxytryptamine (5-HT) (serotonin), substance P, and vasoactive intestinal polypeptide (VIP) demonstrated the multihormonal nature of this tumor.",

author = "Ordonez, {N. G.} and Alberto Ayala and N. Sneige and B. Mackay",

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AU - Ordonez, N. G.

AU - Ayala, Alberto

AU - Sneige, N.

AU - Mackay, B.

PY - 1982/1/1

Y1 - 1982/1/1

N2 - A primary pure testicular carcinoid from a 48-year-old man was examined with antisera raised against various neurohormonal polypeptides. Histochemically, both argyrophil and argentaffin reactions were positive. The immunohistochemical finding of immunoreactive cells for 5-hydroxytryptamine (5-HT) (serotonin), substance P, and vasoactive intestinal polypeptide (VIP) demonstrated the multihormonal nature of this tumor.

AB - A primary pure testicular carcinoid from a 48-year-old man was examined with antisera raised against various neurohormonal polypeptides. Histochemically, both argyrophil and argentaffin reactions were positive. The immunohistochemical finding of immunoreactive cells for 5-hydroxytryptamine (5-HT) (serotonin), substance P, and vasoactive intestinal polypeptide (VIP) demonstrated the multihormonal nature of this tumor.

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Immunohistochemical demonstration of multiple neurohormonal polypeptides in a case of pure testicular carcinoid

Abstract

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