Immunobarriers of the tubotympanum

D. J. Lim, T. F. DeMaria

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


The tubotympanum is protected by an immune system in addition to the mucociliary, secretory (antibacterial substance), and phagocytic defense systems. The immune protection is provided by innate and adaptive immune systems. With the latter, the tubotympanum is protected by both the local (humoral and cellular) and the systemic immunity. The major immunoglobulins involved are IgG, IgM (SIgM), and SIgA, although IgE and IgD may also be involved.

Original languageEnglish (US)
Pages (from-to)355-362
Number of pages8
JournalActa Oto-Laryngologica
Issue number5-6
StatePublished - 1987

ASJC Scopus subject areas

  • Otorhinolaryngology


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