Imaging evaluation of acute chest pain: Systematic review of evidence base and cost-effectiveness

Fabian Bamberg, Roy P. Marcus, Christopher L. Schlett, U. Joseph Schoepf, Thorsten R. Johnson, John W. Nance, Udo Hoffmann, Maximilian F. Reiser, Konstantin Nikolaou

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Given the often inconclusive initial evaluation of patients presenting with acute chest pain in the Emergency Department, advanced imaging techniques have been evaluated in the quest for improving the current standard of care. In this article, we systematically compare and evaluate the available evidence and cost-effectiveness of radionucleotide myocardial perfusion imaging, cardiac computed tomography angiography, and cardiac magnetic resonance imaging using data from PubMed and EMBASE through January 2012. The obtained data were summarized and categorized according to the reached level of evidence and its impact on the decision-making process.

Original languageEnglish (US)
Pages (from-to)289-295
Number of pages7
JournalJournal of Thoracic Imaging
Issue number5
StatePublished - Sep 2012


  • acute chest pain
  • cardiac computed tomography
  • cost-effectiveness
  • evidencebased medicine
  • magnetic resonance imaging
  • myocardial perfusion imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pulmonary and Respiratory Medicine


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