Idiopathic normal-pressure hydrocephalus syndrome: Is it understood? The comprehensive idiopathic normal-pressure hydrocephalus theory (CiNPHT)

Ahmed Ammar, Faisal Abbas, Wisam Al Issawi, Fatima Fakhro, Layla Batarfi, Ahmed Hendam, Mohammed Hasen, Mohammed El Shawarby, Hosam Al Jehani

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

The best description of idiopathic normal-pressure hydrocephalus (iNPH) is it is a multifactorial syndrome and is progressive in nature, while the secondary normal-pressure hydrocephalus (sNPH) is a disease. It has been long striving to reveal the causes, pathophysiology, and best possible of treatment of that syndrome. More than a dozen of concepts and theories have been produced to explain most of the phenomena, which are related to iNPH. Unfortunately, there is no single theory could explain it all. Therefore, we carried on a research to prove the role of venous and small blood vessel ischemia in advancing of this syndrome. We merged the results of this research with the concepts of most of the previous iNPH theories into one theory, which we called “comprehensive idiopathic normal-pressure hydrocephalus syndrome theory.” This concept may provide a wider and deeper understanding of this syndrome and carries within it several suggestions to find new management plans in order to get better outcome.

Original languageEnglish (US)
Title of host publicationHydrocephalus
Subtitle of host publicationWhat Do We Know? And What Do We Still not Know?
PublisherSpringer International Publishing
Pages67-82
Number of pages16
ISBN (Electronic)9783319613048
ISBN (Print)9783319613031
DOIs
StatePublished - Jan 1 2017

Keywords

  • Comprehensive iNPH theory
  • Cortical venous circulationCSF dynamics
  • Idiopathic normal-pressure hydrocephalus

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)
  • Arts and Humanities(all)

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