Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in preclinical leukemia models

Juliana Benito, Marc S. Ramirez, Niki Zacharias Millward, Juliana Velez, Karine G. Harutyunyan, Hongbo Lu, Yue Xi Shi, Polina Matre, Rodrigo Jacamo, Helen Ma, Sergej Konoplev, Teresa McQueen, Andrei Volgin, Marina Protopopova, Hong Mu, Jaehyuk Lee, Pratip K. Bhattacharya, Joseph R. Marszalek, R. Eric Davis, James A. BanksonJorge E. Cortes, Charles P. Hart, Michael Andreeff, Marina Konopleva

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    Pharmacology, Toxicology and Pharmaceutical Science

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    Medicine and Dentistry