TY - JOUR
T1 - Hyperbaric oxygen therapy in the treatment of radiation optic neuropathy
AU - Malik, Amina I.
AU - Golnik, Karl
PY - 2012/6/1
Y1 - 2012/6/1
N2 - Radiation optic neuropathy (RON) is characterized by the rapid onset of painless irreversible vision loss in one or both eyes. We report 4 consecutive patients who presented with unilateral or asymmetric bilateral RON. All had bilateral optic nerve enhancement on MRI and were treated with hyperbaric oxygen (HBO) and oral corticosteroids. In the less affected eye, 2 of the 4 patients had preservation of vision, while in the other 2 patients, vision declined. No patient showed improvement in the more symptomatic eye, and in 2 patients, there was a significant decline in visual acuity. Our findings suggest that prompt treatment with HBO and oral corticosteroids may result in visual preservation in the less affected eye despite the presence of optic nerve enhancement on MRI.
AB - Radiation optic neuropathy (RON) is characterized by the rapid onset of painless irreversible vision loss in one or both eyes. We report 4 consecutive patients who presented with unilateral or asymmetric bilateral RON. All had bilateral optic nerve enhancement on MRI and were treated with hyperbaric oxygen (HBO) and oral corticosteroids. In the less affected eye, 2 of the 4 patients had preservation of vision, while in the other 2 patients, vision declined. No patient showed improvement in the more symptomatic eye, and in 2 patients, there was a significant decline in visual acuity. Our findings suggest that prompt treatment with HBO and oral corticosteroids may result in visual preservation in the less affected eye despite the presence of optic nerve enhancement on MRI.
UR - http://www.scopus.com/inward/record.url?scp=84861814933&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861814933&partnerID=8YFLogxK
U2 - 10.1097/WNO.0b013e3182464c88
DO - 10.1097/WNO.0b013e3182464c88
M3 - Article
C2 - 22286188
AN - SCOPUS:84861814933
VL - 32
SP - 128
EP - 131
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
SN - 1070-8022
IS - 2
ER -