Hybrid textile heart valve prosthesis: Preliminary in vitro evaluation

Antoine Vaesken, Christian Pidancier, Nabil Chakfe, Frederic Heim

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Transcatheter aortic valve implantation (TAVI) is nowadays a popular alternative technique to surgical valve replacement for critical patients. Biological valve tissue has been used in these devices for over a decade now with over 100,000 implantations. However, material degradations due to crimping for catheter insertion purpose have been reported, and with only 6-year follow-up, no information is available about the long-term durability of biological tissue. Moreover, expensive biological tissue harvesting and chemical treatment procedures tend to promote the development of synthetic valve leaflet materials. Textile polyester (PET) material is characterized by outstanding folding and strength properties combined with proven biocompatibility and could therefore be considered as a candidate to replace biological valve leaflets in TAVI devices. Nevertheless, the material should be preferentially partly elastic in order to limit water hammer effects at valve closing time and prevent exaggerated stress from occurring into the stent and the valve. The purpose of the present work is to study in vitro the mechanical as well as the hydrodynamic behavior of a hybrid elastic textile valve device combining non-deformable PET yarn and elastic polyurethane (PU) yarn. The hybrid valve properties are compared with those of a non-elastic textile valve. Testing results show improved hydrodynamic properties with the elastic construction. However, under fatigue conditions, the interaction between PU and PET yarns tends to limit the valve durability.

Original languageEnglish (US)
Pages (from-to)333-339
Number of pages7
JournalBiomedizinische Technik
Volume63
Issue number3
DOIs
StatePublished - Jun 27 2018

Keywords

  • composite
  • heart valve
  • hybrid
  • textile
  • transcatheter
  • transcatheter aortic valve implantation (TAVI)

ASJC Scopus subject areas

  • Biomedical Engineering

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