TY - JOUR
T1 - Hormone replacement therapy and 24-hour blood pressure profile of postmenopausal women
AU - Butkevich, Alexander
AU - Abraham, Carmella
AU - Phillips, Robert A.
N1 - Funding Information:
This work was supported in part by a grant 5MO1 RR00071 for the Mount Sinai General Research Center from the National Center for Research Resources, National Institutes of Health, and by a private grant from Mr. Howard L. Printz.
Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 2000
Y1 - 2000
N2 - Menopause is associated with an increase in blood pressure (BP) and a decrease in physiologic nocturnal BP fall. These factors may play a role in the increased risk of cardiovascular events after menopause. Some studies indicate that transdermal estrogen replacement therapy may help restore the 24-h BP profile, but data on the effect of oral conjugated estrogens are lacking. We compared 24-h ambulatory BP profiles of 42 postmenopausal women not receiving hormone replacement therapy (HRT) and 20 women receiving HRT. HRT was associated with a significant increase in the proportion of dippers (50% in women not receiving HRT and 80% in women receiving HRT, P = .048). Increase in nocturnal dipping may account, in part, for the beneficial cardiovascular effects of HRT. (C) 2000 American Journal of Hypertension, Ltd.
AB - Menopause is associated with an increase in blood pressure (BP) and a decrease in physiologic nocturnal BP fall. These factors may play a role in the increased risk of cardiovascular events after menopause. Some studies indicate that transdermal estrogen replacement therapy may help restore the 24-h BP profile, but data on the effect of oral conjugated estrogens are lacking. We compared 24-h ambulatory BP profiles of 42 postmenopausal women not receiving hormone replacement therapy (HRT) and 20 women receiving HRT. HRT was associated with a significant increase in the proportion of dippers (50% in women not receiving HRT and 80% in women receiving HRT, P = .048). Increase in nocturnal dipping may account, in part, for the beneficial cardiovascular effects of HRT. (C) 2000 American Journal of Hypertension, Ltd.
KW - Blood pressure profile
KW - Hormone replacement therapy
KW - Menopause
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U2 - 10.1016/S0895-7061(00)00284-3
DO - 10.1016/S0895-7061(00)00284-3
M3 - Article
C2 - 10981557
AN - SCOPUS:0033850975
SN - 0895-7061
VL - 13
SP - 1039
EP - 1041
JO - American Journal of Hypertension
JF - American Journal of Hypertension
IS - 9
ER -