Hodgkin's disease associated with central pontine myelinolysis

Murali M. Chintagumpala; Donald H. Mahoney; Kenneth McClain; Zoann E. Dreyer; Marvin A. Fishman; Clark L. Carrol; Charles P. Steuber

doi:10.1002/mpo.2950210416

Hodgkin's disease associated with central pontine myelinolysis

Murali M. Chintagumpala, Donald H. Mahoney, Kenneth McClain, Zoann E. Dreyer, Marvin A. Fishman, Clark L. Carrol, Charles P. Steuber

Research output: Contribution to journal › Article

8 Scopus citations

Abstract

We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.

Original language	English (US)
Pages (from-to)	311-314
Number of pages	4
Journal	Medical and Pediatric Oncology
Volume	21
Issue number	4
DOIs	https://doi.org/10.1002/mpo.2950210416
State	Published - 1993

Keywords

central pontine myelinolysis
Hodgkin's disease
intracranial lesion

ASJC Scopus subject areas

Cancer Research
Oncology
Pediatrics, Perinatology, and Child Health

Access to Document

10.1002/mpo.2950210416

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title = "Hodgkin's disease associated with central pontine myelinolysis",

abstract = "We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.",

keywords = "central pontine myelinolysis, Hodgkin's disease, intracranial lesion",

author = "Chintagumpala, {Murali M.} and Mahoney, {Donald H.} and Kenneth McClain and Dreyer, {Zoann E.} and Fishman, {Marvin A.} and Carrol, {Clark L.} and Steuber, {Charles P.}",

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T1 - Hodgkin's disease associated with central pontine myelinolysis

AU - Chintagumpala, Murali M.

AU - Mahoney, Donald H.

AU - McClain, Kenneth

AU - Dreyer, Zoann E.

AU - Fishman, Marvin A.

AU - Carrol, Clark L.

AU - Steuber, Charles P.

PY - 1993

Y1 - 1993

N2 - We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.

AB - We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.

KW - central pontine myelinolysis

KW - Hodgkin's disease

KW - intracranial lesion

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