HLA-testing and laboratory medicine

Nicholas R. DiPaola; Reinhold Munker; Kerry Atkinson

doi:10.1017/CBO9781139519205.030

HLA-testing and laboratory medicine

Nicholas R. DiPaola, Reinhold Munker, Kerry Atkinson

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Histocompatibility typing HLA-matching or compatibility is the major condition for standard allogeneic transplantation. HLA-testing is generally done on PB leukocytes or lymphocytes. By definition, HLA-matching implies identity at class I and II loci. Recently, most transplant centers switched from serological testing to molecular testing, which offers a higher degree of definition for unrelated transplants. There are four possible scenarios for allogeneic transplantation.

Original language	English (US)
Title of host publication	The BMT Data Book
Subtitle of host publication	Including Cellular Therapy
Publisher	Cambridge University Press
Pages	509-524
Number of pages	16
ISBN (Electronic)	9781139519205
ISBN (Print)	9781107617551
DOIs	https://doi.org/10.1017/CBO9781139519205.030
State	Published - Jan 1 2013

ASJC Scopus subject areas

Medicine(all)

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10.1017/CBO9781139519205.030

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HLA-testing and laboratory medicine

Abstract

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