HIV update. Diagnostic tests and markers of disease progression and response to therapy.

Mancong Zhang, James Versalovic

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

HIV-1 infection continues to present diagnostic and management challenges on a global scale. Multiple testing strategies currently are used for evaluation of patients and infection status. Serologic testing represents the standard for diagnosis of HIV-1 infection. Molecular methods enable screening of the blood supply, detection of vertical transmission, and viral load testing to monitor patients during therapy. Molecular resistance testing facilitates the assessment of viral quasi species and the presence of specific mutations that confer antiviral resistance. Both genotyping and phenotyping approaches have been adopted for HIV-1 drug-resistance testing and enable rational modification of therapies for patients in whom their current regimens are failing.

Original languageEnglish (US)
JournalAmerican Journal of Clinical Pathology
Volume118 Suppl
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'HIV update. Diagnostic tests and markers of disease progression and response to therapy.'. Together they form a unique fingerprint.

Cite this