HITs and misses in 100 years of heparin

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Heparin was discovered 100 years ago, and the heparin-induced thrombocytopenia syndrome was described 40 years ago. That the most powerful anticoagulant of the last century can also produce the most extreme prothrombotic diathesis is but one of the paradoxes that surround heparin-induced thrombocytopenia. Standard treatment is alternative anticoagulation. Advances continue to be made regarding pathophysiology, prevention, and treatment. Currently, an epidemic of overdiagnosis threatens the well-being of patients, so efforts to educate clinicians on when and how to make this diagnosis are pressing.

Original languageEnglish (US)
Pages (from-to)667-673
Number of pages7
JournalHematology
Volume2017
Issue number1
DOIs
StatePublished - Dec 8 2017

ASJC Scopus subject areas

  • Hematology

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