@article{dedfbd50dcb249f087fe26a2874ce3bb,
title = "Histochemical localization of carbonic anhydrase in the inner ear",
abstract = "Carbonic anhydrase was histochemically located in chinchilla inner ear tissues. A strong carbonic anhydrase reaction was observed in the spiral ligament cells, Boettcher's cells, the external sulcus cells, and the stria vascularis (intermediate and/or basal cells). The enzymatic reaction was also positive in the supporting cells of all vestibular sensory epithelia, as well as in the dark cells and transitional cells of the utricle and saccule. Some epithelial cells of the endolymphatic sac were also positive. It is speculated that this enzyme may be involved in: 1) ionic or fluid regulation of the endolymph, 2) removal of CO2 from the inner ear tissue near the sensory cells, and 3) otoconia formation and maintenance.",
keywords = "Carbonic anhydrase, Chinchilla, Histochemistry, Inner ear",
author = "Lim, {David J.} and Christos Karabinas and Trune, {Dennis R.}",
note = "Funding Information: From the Otological Research Laboratories, Department of Otolaryngology, Ohio State University College of Medicine, Columbus, Ohio. Received July 23, 1982. Accepted for publication September 5, 1982. Supported in part by a grant from NASA (NSG-2220), a contract from the US Air Force (F33615-80-C-0506), and a Roessler Research Scholarship to Dr. Karabinas, who participated in this project as a medical student. Presented at the Workshop on Unresolved Research Problems in Meniere's Disease at the Fifth Midwinter Research Meeting, Association for Research in Otolaryngology, St. Petersburg Beach, Fla., January 18-19, 1982 (funded by NINCDS no. NSO8854-12S1). * Professor of Otolaryngology and Anatomy and Director, Otological Research Laboratories. # Resident in the Department of Otolaryngology, University of Minnesota Medical School. r NIH Postdoctoral Fellow (5 P32 NS06211). Address correspondence and reprint requests to Dr, L\]m: 4331 University Hospitals Clinic, 456 Clinic Drive, Columbus, Ohio 43210.",
year = "1983",
month = jan,
day = "2",
doi = "10.1016/S0196-0709(83)80005-2",
language = "English (US)",
volume = "4",
pages = "33--42",
journal = "American Journal of Otolaryngology--Head and Neck Medicine and Surgery",
issn = "0196-0709",
publisher = "W.B. Saunders",
number = "1",
}