Abstract
8-Hydroxyquinolin-N-oxide was found to be a very efficient ligand for the copper-catalyzed hydroxylation of aryl iodides, aryl bromides, or aryl chlorides under mild reaction conditions. This methodology provides a direct transformation of aryl halides to phenols and to alkyl aryl ethers. The inexpensive catalytic system showed great functional group tolerance and excellent selectivity.
Original language | English (US) |
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Pages (from-to) | 4340-4343 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 13 |
Issue number | 16 |
DOIs | |
State | Published - Aug 19 2011 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry