Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

Yuzhen Wang, Yujun Song, Guixian Zhu, Dechen Zhang, Xuewu Liu

Research output: Contribution to journalArticle

24 Scopus citations


More recently, the biomedical applications of MnO2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However, research on a near infrared (NIR) photothermal response of MnO2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin (BSA)-reduced and stabilized MnO2 nanoparticles (BSA-MnO2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.

Original languageEnglish (US)
Pages (from-to)1685-1688
Number of pages4
JournalChinese Chemical Letters
Issue number11
StatePublished - Nov 2018


  • Bovine serum albumin
  • Cancer therapy
  • Manganese dioxide
  • NIR
  • Photothermal

ASJC Scopus subject areas

  • Chemistry(all)

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