TY - JOUR
T1 - Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy
AU - Wang, Yuzhen
AU - Song, Yujun
AU - Zhu, Guixian
AU - Zhang, Dechen
AU - Liu, Xuewu
PY - 2018/11
Y1 - 2018/11
N2 - More recently, the biomedical applications of MnO2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However, research on a near infrared (NIR) photothermal response of MnO2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin (BSA)-reduced and stabilized MnO2 nanoparticles (BSA-MnO2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.
AB - More recently, the biomedical applications of MnO2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However, research on a near infrared (NIR) photothermal response of MnO2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin (BSA)-reduced and stabilized MnO2 nanoparticles (BSA-MnO2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.
KW - Bovine serum albumin
KW - Cancer therapy
KW - Manganese dioxide
KW - NIR
KW - Photothermal
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UR - http://www.scopus.com/inward/citedby.url?scp=85041606596&partnerID=8YFLogxK
U2 - 10.1016/j.cclet.2017.12.004
DO - 10.1016/j.cclet.2017.12.004
M3 - Article
AN - SCOPUS:85041606596
VL - 29
SP - 1685
EP - 1688
JO - Chinese Chemical Letters
JF - Chinese Chemical Letters
SN - 1001-8417
IS - 11
ER -