High-resolution 3D scaffold model for engineered tissue fabrication using a rapid prototyping technique

P. Quadrani, A. Pasini, Monica Mattioli-Belmonte, C. Zannoni, Anna Tampieri, E. Landi, F. Giantomassi, D. Natali, F. Casali, G. Biagini, A. Tomei-Minardi

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Rapid prototyping, automatic image processing (computer-aided design (CAD)) and computer-aided manufacturing techniques are opening new and interesting prospects for medical devices and tissue engineering, especially for hard tissues such as bone. The development of a bone high-resolution scaffold prototype using these techniques is described. The results testify to the fidelity existing between microtomographic reconstruction and CAD. Furthermore, stereolithographic manufacturing of this scaffold, which possesses a high degree of similarity to the starting model as monitored by morphological evaluations (mean diameter 569 ± 147 μm), represents a promising result for regenerative medicine applications.

Original languageEnglish (US)
Pages (from-to)196-199
Number of pages4
JournalMedical and Biological Engineering and Computing
Volume43
Issue number2
DOIs
StatePublished - Mar 1 2005

Keywords

  • Bone-like scaffold
  • CAD/CAM
  • Microtomography
  • Stereolithography
  • Tissue engineering

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management
  • Computer Science Applications
  • Computational Theory and Mathematics

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