High rate of coronary artery abnormalities in adolescents and young adults infected with human immunodeficiency virus early in life

Irene J. Mikhail, Julia B. Purdy, David S. Dimock, Vijaya M. Thomas, Nancy A. Muldoon, Sarah B. Clauss, Russell R. Cross, Roderic I. Pettigrew, Rohan Hazra, Colleen Hadigan, Ahmed M. Gharib

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We completed a cross-sectional study of individuals infected with human immunodeficiency virus in early childhood using cardiac magnetic resonance imaging and magnetic resonance angiography. Coronary artery abnormality (CAA) was defined by the presence of luminal narrowing and irregularity of the coronary vessel wall. More than 50% of participants (14/27) had evidence of CAA. Individuals had a high rate of CAA, suggesting possible early atherosclerosis.

Original languageEnglish (US)
Pages (from-to)712-714
Number of pages3
JournalPediatric Infectious Disease Journal
Volume30
Issue number8
DOIs
StatePublished - Aug 2011

Keywords

  • HIV
  • cardiovascular
  • coronary MRI
  • coronary artery abnormality
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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