High-Dose Vitamin A Therapy for Darier's Disease

J. Raymond Thomas; John P. Cooke; R. K. Winkelmann

doi:10.1001/archderm.1982.01650230019019

High-Dose Vitamin A Therapy for Darier's Disease

J. Raymond Thomas, John P. Cooke, R. K. Winkelmann

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Three patients with Darier's disease were treated with 1 x 10⁶ IU of orally administered vitamin A daily for 14 days. In all patients, 50% to 80% improvement in the skin lesions was noted. Desquamation was minimal, and side effects consisted of drowsiness, mild frontal headache, dry lips, and dry nose. During therapy, all patients had a transient, mild increase in the serum triglyceride level, and two patients had a minimal increase in the serum cholesterol concentration.

Original language	English (US)
Pages (from-to)	891-894
Number of pages	4
Journal	Archives of Dermatology
Volume	118
Issue number	11
DOIs	https://doi.org/10.1001/archderm.1982.01650230019019
State	Published - Nov 1982

ASJC Scopus subject areas

Dermatology

Access to Document

10.1001/archderm.1982.01650230019019

Cite this

@article{6775e2575d3a4266b8c1ec3fd1c2e9b1,

title = "High-Dose Vitamin A Therapy for Darier's Disease",

abstract = "Three patients with Darier's disease were treated with 1 x 106 IU of orally administered vitamin A daily for 14 days. In all patients, 50\% to 80\% improvement in the skin lesions was noted. Desquamation was minimal, and side effects consisted of drowsiness, mild frontal headache, dry lips, and dry nose. During therapy, all patients had a transient, mild increase in the serum triglyceride level, and two patients had a minimal increase in the serum cholesterol concentration.",

author = "Thomas, \{J. Raymond\} and Cooke, \{John P.\} and Winkelmann, \{R. K.\}",

year = "1982",

month = nov,

doi = "10.1001/archderm.1982.01650230019019",

language = "English (US)",

volume = "118",

pages = "891--894",

journal = "Archives of Dermatology",

issn = "0003-987X",

publisher = "American Medical Association",

number = "11",

}

TY - JOUR

T1 - High-Dose Vitamin A Therapy for Darier's Disease

AU - Thomas, J. Raymond

AU - Cooke, John P.

AU - Winkelmann, R. K.

PY - 1982/11

Y1 - 1982/11

N2 - Three patients with Darier's disease were treated with 1 x 106 IU of orally administered vitamin A daily for 14 days. In all patients, 50% to 80% improvement in the skin lesions was noted. Desquamation was minimal, and side effects consisted of drowsiness, mild frontal headache, dry lips, and dry nose. During therapy, all patients had a transient, mild increase in the serum triglyceride level, and two patients had a minimal increase in the serum cholesterol concentration.

AB - Three patients with Darier's disease were treated with 1 x 106 IU of orally administered vitamin A daily for 14 days. In all patients, 50% to 80% improvement in the skin lesions was noted. Desquamation was minimal, and side effects consisted of drowsiness, mild frontal headache, dry lips, and dry nose. During therapy, all patients had a transient, mild increase in the serum triglyceride level, and two patients had a minimal increase in the serum cholesterol concentration.

UR - https://www.scopus.com/pages/publications/0019936212

UR - https://www.scopus.com/inward/citedby.url?scp=0019936212&partnerID=8YFLogxK

U2 - 10.1001/archderm.1982.01650230019019

DO - 10.1001/archderm.1982.01650230019019

M3 - Article

C2 - 7138044

AN - SCOPUS:0019936212

SN - 0003-987X

VL - 118

SP - 891

EP - 894

JO - Archives of Dermatology

JF - Archives of Dermatology

IS - 11

ER -

High-Dose Vitamin A Therapy for Darier's Disease

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this