Heterotopic heart transplantation and native heart ventricular arrhythmias

Carol Kotliar; Frank W. Smart; Michael E. Sekela; Antonio Pacifico; Craig M. Pratt; George P. Noon; Michael E. DeBakey; James B. Young

doi:10.1016/0003-4975(91)91025-Q

Heterotopic heart transplantation and native heart ventricular arrhythmias

Carol Kotliar, Frank W. Smart, Michael E. Sekela, Antonio Pacifico, Craig M. Pratt, George P. Noon, Michael E. DeBakey, James B. Young

Research output: Contribution to journal › Article

13 Scopus citations

Abstract

Heterotopic heart transplantation has been said to be contraindicated in patients with serious native heart arrhythmias that produce hemodynamic instability. Placement of heterotopic allografts, however, can theoretically act as a biological biventricular assist device to provide hemodynamic support during these unstable rhythms. Further, this operation might beneficially alter the hemodynamic milieu of heart failure such that the arrhythmias are ameliorated. Described is our experience with 4 patients with heart failure receiving heterotopic cardiac allografts, documenting changes in native heart arrhythmia that occurred. These cases demonstrate that heterotopic grafts can adequately sustain hemodynamics during malignant native heart dysrhythmia. We believe native heart ventricular arrhythmias are not a contraindication to heterotopic heart transplantation.

Original language	English (US)
Pages (from-to)	987-991
Number of pages	5
Journal	The Annals of thoracic surgery
Volume	51
Issue number	6
DOIs	https://doi.org/10.1016/0003-4975(91)91025-Q
State	Published - Jun 1991

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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title = "Heterotopic heart transplantation and native heart ventricular arrhythmias",

abstract = "Heterotopic heart transplantation has been said to be contraindicated in patients with serious native heart arrhythmias that produce hemodynamic instability. Placement of heterotopic allografts, however, can theoretically act as a biological biventricular assist device to provide hemodynamic support during these unstable rhythms. Further, this operation might beneficially alter the hemodynamic milieu of heart failure such that the arrhythmias are ameliorated. Described is our experience with 4 patients with heart failure receiving heterotopic cardiac allografts, documenting changes in native heart arrhythmia that occurred. These cases demonstrate that heterotopic grafts can adequately sustain hemodynamics during malignant native heart dysrhythmia. We believe native heart ventricular arrhythmias are not a contraindication to heterotopic heart transplantation.",

author = "Carol Kotliar and Smart, {Frank W.} and Sekela, {Michael E.} and Antonio Pacifico and Pratt, {Craig M.} and Noon, {George P.} and DeBakey, {Michael E.} and Young, {James B.}",

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AU - Kotliar, Carol

AU - Smart, Frank W.

AU - Sekela, Michael E.

AU - Pacifico, Antonio

AU - Pratt, Craig M.

AU - Noon, George P.

AU - DeBakey, Michael E.

AU - Young, James B.

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AB - Heterotopic heart transplantation has been said to be contraindicated in patients with serious native heart arrhythmias that produce hemodynamic instability. Placement of heterotopic allografts, however, can theoretically act as a biological biventricular assist device to provide hemodynamic support during these unstable rhythms. Further, this operation might beneficially alter the hemodynamic milieu of heart failure such that the arrhythmias are ameliorated. Described is our experience with 4 patients with heart failure receiving heterotopic cardiac allografts, documenting changes in native heart arrhythmia that occurred. These cases demonstrate that heterotopic grafts can adequately sustain hemodynamics during malignant native heart dysrhythmia. We believe native heart ventricular arrhythmias are not a contraindication to heterotopic heart transplantation.

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