Heterotopic heart transplantation and native heart ventricular arrhythmias

Carol Kotliar, Frank W. Smart, Michael E. Sekela, Antonio Pacifico, Craig M. Pratt, George P. Noon, Michael E. DeBakey, James B. Young

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Heterotopic heart transplantation has been said to be contraindicated in patients with serious native heart arrhythmias that produce hemodynamic instability. Placement of heterotopic allografts, however, can theoretically act as a biological biventricular assist device to provide hemodynamic support during these unstable rhythms. Further, this operation might beneficially alter the hemodynamic milieu of heart failure such that the arrhythmias are ameliorated. Described is our experience with 4 patients with heart failure receiving heterotopic cardiac allografts, documenting changes in native heart arrhythmia that occurred. These cases demonstrate that heterotopic grafts can adequately sustain hemodynamics during malignant native heart dysrhythmia. We believe native heart ventricular arrhythmias are not a contraindication to heterotopic heart transplantation.

Original languageEnglish (US)
Pages (from-to)987-991
Number of pages5
JournalThe Annals of thoracic surgery
Issue number6
StatePublished - Jun 1991

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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