Herpes Simplex Vegetans Presenting as an Eyelid Mass

Lauren S. Blieden, Patricia Chévez-Barrios, Michael T. Yen

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


A 16-year-old girl with congenital T-cell immunodeficiency presented with a 2-month history of an enlarging lower eyelid mass. After complete excision of the mass, the lesion was noted to recur. Histologic and immunohistochemical analysis of the excised mass revealed infection with herpes simplex virus types 1 and 2 with exuberant inflammatory reaction and granulation tissue consistent with the diagnosis of herpes simplex vegetans. Treatment with valacyclovir resulted in complete resolution of the remaining lesions. Herpes simplex vegetans should be included in the clinical and histopathologic differential for rapidly growing cutaneous masses in patients with immunodeficiency.

Original languageEnglish (US)
Pages (from-to)e58-e59
JournalOphthalmic Plastic and Reconstructive Surgery
Issue number3
StatePublished - Jan 1 2011

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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