Hepatocellular Carcinoma

Sahin Lacin, Asif Rashid, Yun Shin Chun, Bruno Calazans Odisio, Eugene J. Koay, Reham Abdel-Wahab, Ahmed O. Kaseb

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Worldwide, hepatocellular carcinoma (HCC) is the sixth most common cancer and the second most common cause of cancer mortality, with a very poor survival rate. Many factors increasing the risk of HCC are classified into two groups: preventable and non-preventable. Unfortunately, HCC incidence is steadily increasing throughout the world. Therefore, many different kinds of HCC treatment are being evaluated to establish the optimal modality, reduce the development of new tumors, and prevent recurrence after surgical resection or liver transplantation. Basically, the treatment options for HCC are categorized as surgical or nonsurgical. Surgical therapies encompass resection and liver transplantation, whereas nonsurgical therapies include ablation techniques, transarterial therapies, irradiation, and systemic therapy including chemotherapy and molecularly targeted therapy.

Original languageEnglish (US)
Title of host publicationTextbook of Gastrointestinal Oncology
PublisherSpringer Science+Business Media
Pages207-234
Number of pages28
ISBN (Electronic)9783030188900
ISBN (Print)9783030188887
DOIs
StatePublished - Jan 1 2019

Keywords

  • Ablation
  • Hepatocellular carcinoma
  • Liver surgery
  • Molecularly targeted therapy
  • Radioembolization
  • Systemic chemotherapy
  • Transarterial chemoembolization

ASJC Scopus subject areas

  • General Medicine

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