Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers

Wolf Szmuness; Alfred M. Prince; George F. Grady; Margaret K. Mann; Richard W. Levine; Eli A. Friedman; Martin J. Jacobs; Adeline Josephson; Seymour Ribot; Fred L. Shapiro; Kurt H. Stenzel; Wadi N. Suki; Girish Vyas

doi:10.1001/jama.1974.03230210013003

Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers

Wolf Szmuness, Alfred M. Prince, George F. Grady, Margaret K. Mann, Richard W. Levine, Eli A. Friedman, Martin J. Jacobs, Adeline Josephson, Seymour Ribot, Fred L. Shapiro, Kurt H. Stenzel, Wadi N. Suki, Girish Vyas

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Abstract

Five hundred eighty-three patients and 451 medical personnel of 15 hemodialysis centers were surveyed for hepatitis B infections. Hepatitis B antigen (HB Ag) was detected in 16.8% of the patients and in 2.4% of the medical staff; specific antibody to HB Ag (HB Ab) was detected in 34.0% and 31.3%, respectively. The cumulative prevalence of HB Ag and HB Ab varied widely among the centers. The prevalence of HB Ag or HB Ab in patients was related to duration of dialysis treatment, but not to blood transfusions. Significant differences in prevalence of serologic indicators of hepatitis B infection among various staff categories were not observed. Sixty-one percent of family contacts of dialysis patients with a history of hepatitis B infection were found to have HB Ag or HB Ab.

Original language	English (US)
Pages (from-to)	901-906
Number of pages	6
Journal	JAMA: The Journal of the American Medical Association
Volume	227
Issue number	8
DOIs	https://doi.org/10.1001/jama.1974.03230210013003
State	Published - Feb 25 1974

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General Medicine

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Szmuness, W., Prince, A. M., Grady, G. F., Mann, M. K., Levine, R. W., Friedman, E. A., Jacobs, M. J., Josephson, A., Ribot, S., Shapiro, F. L., Stenzel, K. H., Suki, W. N., & Vyas, G. (1974). Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers. JAMA: The Journal of the American Medical Association, 227(8), 901-906. https://doi.org/10.1001/jama.1974.03230210013003

Szmuness, W, Prince, AM, Grady, GF, Mann, MK, Levine, RW, Friedman, EA, Jacobs, MJ, Josephson, A, Ribot, S, Shapiro, FL, Stenzel, KH, Suki, WN & Vyas, G 1974, 'Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers', JAMA: The Journal of the American Medical Association, vol. 227, no. 8, pp. 901-906. https://doi.org/10.1001/jama.1974.03230210013003

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abstract = "Five hundred eighty-three patients and 451 medical personnel of 15 hemodialysis centers were surveyed for hepatitis B infections. Hepatitis B antigen (HB Ag) was detected in 16.8% of the patients and in 2.4% of the medical staff; specific antibody to HB Ag (HB Ab) was detected in 34.0% and 31.3%, respectively. The cumulative prevalence of HB Ag and HB Ab varied widely among the centers. The prevalence of HB Ag or HB Ab in patients was related to duration of dialysis treatment, but not to blood transfusions. Significant differences in prevalence of serologic indicators of hepatitis B infection among various staff categories were not observed. Sixty-one percent of family contacts of dialysis patients with a history of hepatitis B infection were found to have HB Ag or HB Ab.",

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AU - Levine, Richard W.

AU - Friedman, Eli A.

AU - Jacobs, Martin J.

AU - Josephson, Adeline

AU - Ribot, Seymour

AU - Shapiro, Fred L.

AU - Stenzel, Kurt H.

AU - Suki, Wadi N.

AU - Vyas, Girish

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AB - Five hundred eighty-three patients and 451 medical personnel of 15 hemodialysis centers were surveyed for hepatitis B infections. Hepatitis B antigen (HB Ag) was detected in 16.8% of the patients and in 2.4% of the medical staff; specific antibody to HB Ag (HB Ab) was detected in 34.0% and 31.3%, respectively. The cumulative prevalence of HB Ag and HB Ab varied widely among the centers. The prevalence of HB Ag or HB Ab in patients was related to duration of dialysis treatment, but not to blood transfusions. Significant differences in prevalence of serologic indicators of hepatitis B infection among various staff categories were not observed. Sixty-one percent of family contacts of dialysis patients with a history of hepatitis B infection were found to have HB Ag or HB Ab.

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Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers

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