Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers

Wolf Szmuness, Alfred M. Prince, George F. Grady, Margaret K. Mann, Richard W. Levine, Eli A. Friedman, Martin J. Jacobs, Adeline Josephson, Seymour Ribot, Fred L. Shapiro, Kurt H. Stenzel, Wadi N. Suki, Girish Vyas

Research output: Contribution to journalArticlepeer-review

152 Scopus citations


Five hundred eighty-three patients and 451 medical personnel of 15 hemodialysis centers were surveyed for hepatitis B infections. Hepatitis B antigen (HB Ag) was detected in 16.8% of the patients and in 2.4% of the medical staff; specific antibody to HB Ag (HB Ab) was detected in 34.0% and 31.3%, respectively. The cumulative prevalence of HB Ag and HB Ab varied widely among the centers. The prevalence of HB Ag or HB Ab in patients was related to duration of dialysis treatment, but not to blood transfusions. Significant differences in prevalence of serologic indicators of hepatitis B infection among various staff categories were not observed. Sixty-one percent of family contacts of dialysis patients with a history of hepatitis B infection were found to have HB Ag or HB Ab.

Original languageEnglish (US)
Pages (from-to)901-906
Number of pages6
JournalJAMA: The Journal of the American Medical Association
Issue number8
StatePublished - Feb 25 1974

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Hepatitis B Infection: A Point-Prevalence Study in 15 US Hemodialysis Centers'. Together they form a unique fingerprint.

Cite this