Hemophagocytic syndrome after Kawasaki disease

Debra L. Palazzi; Kenneth L. McClain; Sheldon Kaplan

doi:10.1097/00006454-200307000-00021

Hemophagocytic syndrome after Kawasaki disease

Debra L. Palazzi, Kenneth L. McClain, Sheldon Kaplan

Research Institute

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Hemophagocytic syndrome (HPS) is a rare and life-threatening disease in which a generalized histiocytic proliferation results in hemophagocytosis and up-regulation of inflammatory cytokines. This syndrome has been associated with infections, malignancy, drugs and immunologic triggers such as Kawasaki disease (KD). We describe the clinical and laboratory features of two children with HPS after KD and review the three previously reported pediatric cases of recrudescence of KD leading to HPS.

Original language	English (US)
Pages (from-to)	663-666
Number of pages	4
Journal	Pediatric Infectious Disease Journal
Volume	22
Issue number	7
DOIs	https://doi.org/10.1097/00006454-200307000-00021
State	Published - Jul 1 2003

Keywords

Hemophagocytic syndrome
Kawasaki disease

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)

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10.1097/00006454-200307000-00021

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AU - McClain, Kenneth L.

AU - Kaplan, Sheldon

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AB - Hemophagocytic syndrome (HPS) is a rare and life-threatening disease in which a generalized histiocytic proliferation results in hemophagocytosis and up-regulation of inflammatory cytokines. This syndrome has been associated with infections, malignancy, drugs and immunologic triggers such as Kawasaki disease (KD). We describe the clinical and laboratory features of two children with HPS after KD and review the three previously reported pediatric cases of recrudescence of KD leading to HPS.

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Hemophagocytic syndrome after Kawasaki disease

Abstract

Keywords

ASJC Scopus subject areas

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