Hemangiopericytoma of the Thyroid:An Unusual Spindle Cell Lesion

Mary L. Ostrowski; Joiner Cartwright; Joyce E. Maldonado; Dina Mody; Virginia A. Livolsi

doi:10.1177/106689699500200408

Hemangiopericytoma of the Thyroid:An Unusual Spindle Cell Lesion

Mary L. Ostrowski, Joiner Cartwright, Joyce E. Maldonado, Dina Mody, Virginia A. Livolsi

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 52-year-old woman presented with a painless right thyroid mass of 4 months duration, with a recent increase in size in the last few weeks. The neoplasm was characterized by bland spindle cells with a low mitotic rate arranged around vascular elements of variable shape and caliber. Multiple immunohistochemical stains failed to show evidence of epithelial. neuroendocrine, or specific mesenchymal differentiation. Electron microscopic studies revealed spindle cells with micropinocytotic vesicles, surrounded by variable but sometimes abundant basement lamina-like material. To the authors' knowledge, this is the first report of a typical hemangiopericytoma of the thyroid gland. This lesion must be distinguished from epithelial and neuroendocrine tumors with spindle cells and from other mesenchymal neoplasms that may occur in the thyroid.

Original language	English (US)
Pages (from-to)	311-317
Number of pages	7
Journal	International Journal of Surgical Pathology
Volume	2
Issue number	4
DOIs	https://doi.org/10.1177/106689699500200408
State	Published - Apr 1995

Keywords

Electron microscopy
Hemangiopericytoma
Immunohistochemistry
Thyroid

ASJC Scopus subject areas

Anatomy
Pathology and Forensic Medicine
Surgery

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10.1177/106689699500200408

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title = "Hemangiopericytoma of the Thyroid:An Unusual Spindle Cell Lesion",

abstract = "A 52-year-old woman presented with a painless right thyroid mass of 4 months duration, with a recent increase in size in the last few weeks. The neoplasm was characterized by bland spindle cells with a low mitotic rate arranged around vascular elements of variable shape and caliber. Multiple immunohistochemical stains failed to show evidence of epithelial. neuroendocrine, or specific mesenchymal differentiation. Electron microscopic studies revealed spindle cells with micropinocytotic vesicles, surrounded by variable but sometimes abundant basement lamina-like material. To the authors' knowledge, this is the first report of a typical hemangiopericytoma of the thyroid gland. This lesion must be distinguished from epithelial and neuroendocrine tumors with spindle cells and from other mesenchymal neoplasms that may occur in the thyroid.",

keywords = "Electron microscopy, Hemangiopericytoma, Immunohistochemistry, Thyroid",

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AU - Ostrowski, Mary L.

AU - Cartwright, Joiner

AU - Maldonado, Joyce E.

AU - Mody, Dina

AU - Livolsi, Virginia A.

PY - 1995/4

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N2 - A 52-year-old woman presented with a painless right thyroid mass of 4 months duration, with a recent increase in size in the last few weeks. The neoplasm was characterized by bland spindle cells with a low mitotic rate arranged around vascular elements of variable shape and caliber. Multiple immunohistochemical stains failed to show evidence of epithelial. neuroendocrine, or specific mesenchymal differentiation. Electron microscopic studies revealed spindle cells with micropinocytotic vesicles, surrounded by variable but sometimes abundant basement lamina-like material. To the authors' knowledge, this is the first report of a typical hemangiopericytoma of the thyroid gland. This lesion must be distinguished from epithelial and neuroendocrine tumors with spindle cells and from other mesenchymal neoplasms that may occur in the thyroid.

AB - A 52-year-old woman presented with a painless right thyroid mass of 4 months duration, with a recent increase in size in the last few weeks. The neoplasm was characterized by bland spindle cells with a low mitotic rate arranged around vascular elements of variable shape and caliber. Multiple immunohistochemical stains failed to show evidence of epithelial. neuroendocrine, or specific mesenchymal differentiation. Electron microscopic studies revealed spindle cells with micropinocytotic vesicles, surrounded by variable but sometimes abundant basement lamina-like material. To the authors' knowledge, this is the first report of a typical hemangiopericytoma of the thyroid gland. This lesion must be distinguished from epithelial and neuroendocrine tumors with spindle cells and from other mesenchymal neoplasms that may occur in the thyroid.

KW - Electron microscopy

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KW - Immunohistochemistry

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Hemangiopericytoma of the Thyroid:An Unusual Spindle Cell Lesion

Abstract

Keywords

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