@article{2ddf9999d5a3444a8b0ee6de98240b38,
title = "Heightened early-attentional stimulus orienting and impulsive action in men with antisocial personality disorder",
abstract = "We tested whether enhanced stimulus orienting operationalized as N1 and P2 auditory evoked potentials to increasing loudness (50–90 dB clicks) could be associated with trait impulsivity (Barratt Impulsiveness Scale, BIS-11), impulsive action (commission error on the Immediate Memory Task), or impulsive choice (immediate responses on temporal discounting tasks). We measured N1 and P2 loudness sensitivity in a passive listening task as linear intensity–sensitivity slopes in 36 men with antisocial personality disorder with a history of conviction for criminal conduct and 16 healthy control men. Across all subjects, regression analyses revealed that a steeper P2 slope predicted higher IMT commission error/correct detection ratio, and lower stimulus discriminability (A-prime). These associations were also found within both groups. These relationships suggest an association between enhanced early stimulus orienting (P2), impulsive action (response inhibition), and impaired signal–noise discriminability (A-prime).",
keywords = "Aggression, Augmenting–reducing, Conduct disorder, Crime, Evoked potential, Impulsivity",
author = "Marijn Lijffijt and Lane, {Scott D.} and Mathew, {Sanjay J.} and Stanford, {Matthew S.} and Swann, {Alan C.}",
note = "Funding Information: Acknowledgments This study was supported in part by the Pat R Rutherford, Jr Chair in Psychiatry (ACS) and by National Institute for Mental Health grants RO1-MH 69944 (ACS), and UL1-RR024148 (CTSA) (General Clinical Research Center UT Houston). This work was performed at the University of Texas Health Science Center at Houston. Sponsors were not involved in study design, data analysis, or decision to publish the data. We thank Michelle D. Acas, BA, Joseph L. Alcorn 3rd, Ph.D., Blake Cox, BA, Lorina Maili, MS, Colt Meier, Ph.D., Leslie M. Paith, BA, Irshad N. Prasla, BSc, Nuvan Rathnayaka, BA, and Tammy J. Souter, RN, APRN, PMH, NP, BC for their help with subject recruitment and assessment. Funding Information: This study was supported in part by the Pat R Rutherford, Jr Chair in Psychiatry (ACS) and by National Institute for Mental Health grants RO1-MH 69944 (ACS), and UL1-RR024148 (CTSA) (General Clinical Research Center UT Houston). This work was performed at the University of Texas Health Science Center at Houston. Sponsors were not involved in study design, data analysis, or decision to publish the data. We thank Michelle D. Acas, BA, Joseph L. Alcorn 3rd, Ph.D., Blake Cox, BA, Lorina Maili, MS, Colt Meier, Ph.D., Leslie M. Paith, BA, Irshad N. Prasla, BSc, Nuvan Rathnayaka, BA, and Tammy J. Souter, RN, APRN, PMH, NP, BC for their help with subject recruitment and assessment. On behalf of all authors, the corresponding author states that there is no conflict of interest. Publisher Copyright: {\textcopyright} 2016, Springer-Verlag Berlin Heidelberg.",
year = "2017",
month = oct,
day = "1",
doi = "10.1007/s00406-016-0734-1",
language = "English (US)",
volume = "267",
pages = "697--707",
journal = "European Archives of Psychiatry and Clinical Neuroscience",
issn = "0940-1334",
publisher = "Springer Verlag",
number = "7",
}