Heart failure in systemic lupus erythematosus

Bishnu P. Dhakal; Chang H. Kim; Sadeer G. Al-Kindi; Guilherme H. Oliveira

doi:10.1016/j.tcm.2017.08.015

Heart failure in systemic lupus erythematosus

Bishnu P. Dhakal, Chang H. Kim, Sadeer G. Al-Kindi, Guilherme H. Oliveira

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a constellation of cardiovascular (CV) and non-CV manifestations. Even though CV complications such as accelerated atherosclerosis and elevated risk of myocardial infarction (MI) have been recognized for many years, there is limited evidence regarding SLE and its association with heart failure (HF). Traditional risk factors of atherosclerotic CV disease, as well as various SLE manifestations and therapies, independently or together, increase the risk of HF in this population. There is a need for sufficiently powered intervention studies focusing on specific risk factors to improve CV outcomes in SLE patients.

Original language	English (US)
Pages (from-to)	187-197
Number of pages	11
Journal	Trends in Cardiovascular Medicine
Volume	28
Issue number	3
DOIs	https://doi.org/10.1016/j.tcm.2017.08.015
State	Published - Apr 2018

Keywords

Cardiovascular risk factors
Heart failure
Lupus
Systemic lupus erythematosus

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.tcm.2017.08.015

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title = "Heart failure in systemic lupus erythematosus",

abstract = "Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a constellation of cardiovascular (CV) and non-CV manifestations. Even though CV complications such as accelerated atherosclerosis and elevated risk of myocardial infarction (MI) have been recognized for many years, there is limited evidence regarding SLE and its association with heart failure (HF). Traditional risk factors of atherosclerotic CV disease, as well as various SLE manifestations and therapies, independently or together, increase the risk of HF in this population. There is a need for sufficiently powered intervention studies focusing on specific risk factors to improve CV outcomes in SLE patients.",

keywords = "Cardiovascular risk factors, Heart failure, Lupus, Systemic lupus erythematosus",

author = "Dhakal, {Bishnu P.} and Kim, {Chang H.} and Al-Kindi, {Sadeer G.} and Oliveira, {Guilherme H.}",

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T1 - Heart failure in systemic lupus erythematosus

AU - Dhakal, Bishnu P.

AU - Kim, Chang H.

AU - Al-Kindi, Sadeer G.

AU - Oliveira, Guilherme H.

PY - 2018/4

Y1 - 2018/4

N2 - Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a constellation of cardiovascular (CV) and non-CV manifestations. Even though CV complications such as accelerated atherosclerosis and elevated risk of myocardial infarction (MI) have been recognized for many years, there is limited evidence regarding SLE and its association with heart failure (HF). Traditional risk factors of atherosclerotic CV disease, as well as various SLE manifestations and therapies, independently or together, increase the risk of HF in this population. There is a need for sufficiently powered intervention studies focusing on specific risk factors to improve CV outcomes in SLE patients.

AB - Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a constellation of cardiovascular (CV) and non-CV manifestations. Even though CV complications such as accelerated atherosclerosis and elevated risk of myocardial infarction (MI) have been recognized for many years, there is limited evidence regarding SLE and its association with heart failure (HF). Traditional risk factors of atherosclerotic CV disease, as well as various SLE manifestations and therapies, independently or together, increase the risk of HF in this population. There is a need for sufficiently powered intervention studies focusing on specific risk factors to improve CV outcomes in SLE patients.

KW - Cardiovascular risk factors

KW - Heart failure

KW - Lupus

KW - Systemic lupus erythematosus

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JO - Trends in Cardiovascular Medicine

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Heart failure in systemic lupus erythematosus

Abstract

Keywords

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