Harmonic scalpel versus flexible CO2 laser for tongue resection: A histopathological analysis of thermal damage in human cadavers

Duncan F. Hanby, Grayson Gremillion, Arthur W. Zieske, Bridget Loehn, Richard Whitworth, Tamir Wolf, Anagha C. Kakade, Rohan R. Walvekar

Research output: Contribution to journalArticle

Abstract

Objectives: To compare thermal damage caused by Harmonic scalpel and CO2 laser to cadaveric tongue. Methods: Two fresh human cadaver heads were enrolled for the study. Oral tongue was exposed and incisions were made in the tongue akin to a tongue tumor resection using the harmonic scalpel and flexible C02 laser fiber at various settings recommended for surgery. The margins of resection were sampled, labeled, and sent for pathological analysis to assess depth of thermal damage calculated in millimeters. The pathologist was blinded to the surgical tool used. Control tongue tissue was also sent as a baseline for comparison. Results: Three tongue samples were studied to assess depth of thermal damage by harmonic scalpel. The mean depth of thermal damage was 0.69 mm, (range, 0.51-0.82 mm). Five tongue samples were studied to assess depth of thermal damage by CO2 laser. The mean depth of thermal damage was 0.3mm, (range, 0.22 to 0.43mm). As expected, control samples showed 0 mm of thermal damage. There was a statistically significant difference between the depth of thermal injury to tongue resection margins by harmonic scalpel as compared to CO2 laser, (p=0.003). Conclusion: In a cadaveric model, flexible CO2 laser fiber causes less depth of thermal damage when compared with harmonic scalpel at settings utilized in our study. However, the relevance of this information in terms of wound healing, hemostasis, safety, costeffectiveness, and surgical outcomes needs to be further studied in clinical settings.

Original languageEnglish (US)
Pages (from-to)S369
JournalLaryngoscope
Volume121
Issue numberSUPPL. 5
DOIs
StatePublished - 2011

ASJC Scopus subject areas

  • Otorhinolaryngology

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