Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

Yuan Li; Xuefeng Xia; Jing Zhang; Zhiqiang Song; Liya Zhou; Yaopeng Zhang; Yonghui Huang; Yanyan Shi; Eamonn M M Quigley; Shigang Ding

doi:10.5114/pg.2015.48995

Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

Yuan Li, Xuefeng Xia, Jing Zhang, Zhiqiang Song, Liya Zhou, Yaopeng Zhang, Yonghui Huang, Yanyan Shi, Eamonn M M Quigley, Shigang Ding

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.

Original language	English (US)
Pages (from-to)	78-82
Number of pages	5
Journal	Przeglad Gastroenterologiczny
Volume	10
Issue number	2
DOIs	https://doi.org/10.5114/pg.2015.48995
State	Published - 2015

Keywords

Cytomegalovirus
Epstein-Barr virus
Haemophagocytic lymphohistiocytosis
Inflammatory bowel disease
Thiopurines

ASJC Scopus subject areas

Gastroenterology

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title = "Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection",

abstract = "Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.",

keywords = "Cytomegalovirus, Epstein-Barr virus, Haemophagocytic lymphohistiocytosis, Inflammatory bowel disease, Thiopurines",

author = "Yuan Li and Xuefeng Xia and Jing Zhang and Zhiqiang Song and Liya Zhou and Yaopeng Zhang and Yonghui Huang and Yanyan Shi and Quigley, {Eamonn M M} and Shigang Ding",

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T1 - Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

AU - Li, Yuan

AU - Xia, Xuefeng

AU - Zhang, Jing

AU - Song, Zhiqiang

AU - Zhou, Liya

AU - Zhang, Yaopeng

AU - Huang, Yonghui

AU - Shi, Yanyan

AU - Quigley, Eamonn M M

AU - Ding, Shigang

PY - 2015

Y1 - 2015

N2 - Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.

AB - Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines.

KW - Cytomegalovirus

KW - Epstein-Barr virus

KW - Haemophagocytic lymphohistiocytosis

KW - Inflammatory bowel disease

KW - Thiopurines

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Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection

Abstract

Keywords

ASJC Scopus subject areas

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