H1N1-associated acute retinitis

Lana Rifkin, Shlomit Schaal

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Purpose: To present the first reported case of bilateral H 1N1-associated acute retinitis and its successful treatment. Design: Interventional case report. Methods: A 41-year-old HIV-positive male presented with acute vision loss, panuveitis, and retinitis. A diagnostic and therapeutic vitrectomy with intravitreal injection of vancomycin and ganciclovir and endolaser was performed. One month later, the patient returned with similar symptoms in the fellow eye and underwent the same procedure. Results: ELISA immunoassay revealed H1N1 antibodies in both the vitreous and serum. PCR for herpes viruses included HSV, CMV, and VZV. Bacterial and fungal cultures were negative. On 1-year follow-up, the vision remained 20/20 in both eyes without evidence of recurrent inflammation. Conclusions: H1N1 should be included in the differential diagnosis of any patient with a history of recent influenza A (H1N1) infection and acute retinitis. H1N 1 may carry a better prognosis than other viruses causing acute retinitis.

Original languageEnglish (US)
Pages (from-to)230-232
Number of pages3
JournalOcular Immunology and Inflammation
Volume20
Issue number3
DOIs
StatePublished - Jun 2012

Keywords

  • H1N1
  • Influenza A
  • Intravitreal antibiotics
  • Intravitreal biopsy
  • Retinitis
  • Viral
  • Vitrectomy

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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