Glycemic Control and Stress Ulcer Prophylaxis

Deepa Gotur, Janice L. Zimmerman

Research output: Chapter in Book/Report/Conference proceedingChapter


The glycemic state in sepsis is a complex interplay of multiple factors leading to glucose dysregulation and hyperglycemia. The recent Surviving Sepsis Campaign 2021 guidelines strongly recommend initiation of insulin therapy for glucose levels >180mg/dL (10mmol/L) with a typical target blood glucose range of 144–180mg/dL (8–10mmol/L). Patients with sepsis or septic shock may have several risk factors for stress ulcers and bleeding. Current guidelines suggest stress ulcer prophylaxis for patients with sepsis who have risk factors for gastrointestinal bleeding. Either proton pump inhibitors or histamine H-2 receptor antagonists can be used for stress ulcer prophylaxis.

Original languageEnglish (US)
Title of host publicationThe Sepsis Codex
Number of pages9
ISBN (Electronic)9780323882712
ISBN (Print)9780323882804
StatePublished - Jan 1 2022


  • Glycemia
  • Hyperglycemia
  • Sepsis
  • Stress ulcer prophylaxis

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Glycemic Control and Stress Ulcer Prophylaxis'. Together they form a unique fingerprint.

Cite this