TY - JOUR
T1 - Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension
AU - Faustinella, Fabrizia
AU - Uzoh, Christian
AU - Sheikh-Hamad, David
AU - Truong, Luan
AU - Olivero, Juan J.
PY - 1997/12
Y1 - 1997/12
N2 - Glomerulomegaly is a histologic finding present in idiopathic pulmonary hypertension, congenital cyanotic heart disease, morbid obesity associated with sleep apnea syndrome, sickle cell disease, and polycythemic states. This study examines the case of a 34-yr-old woman with idiopathic pulmonary artery hypertension who presented with nephrotic-range proteinuria. Kidney biopsy revealed enlarged glomeruli with mesangial-proliferative glomerulonephritis. A review of the pertinent literature and a discussion of the proposed pathophysiologic mechanisms leading to glomerulomegaly are presented.
AB - Glomerulomegaly is a histologic finding present in idiopathic pulmonary hypertension, congenital cyanotic heart disease, morbid obesity associated with sleep apnea syndrome, sickle cell disease, and polycythemic states. This study examines the case of a 34-yr-old woman with idiopathic pulmonary artery hypertension who presented with nephrotic-range proteinuria. Kidney biopsy revealed enlarged glomeruli with mesangial-proliferative glomerulonephritis. A review of the pertinent literature and a discussion of the proposed pathophysiologic mechanisms leading to glomerulomegaly are presented.
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U2 - 10.1681/asn.v8121966
DO - 10.1681/asn.v8121966
M3 - Article
C2 - 9402101
AN - SCOPUS:0031430419
SN - 1046-6673
VL - 8
SP - 1966
EP - 1970
JO - Journal of the American Society of Nephrology
JF - Journal of the American Society of Nephrology
IS - 12
ER -