Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension

Fabrizia Faustinella, Christian Uzoh, David Sheikh-Hamad, Luan Truong, Juan J. Olivero

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Glomerulomegaly is a histologic finding present in idiopathic pulmonary hypertension, congenital cyanotic heart disease, morbid obesity associated with sleep apnea syndrome, sickle cell disease, and polycythemic states. This study examines the case of a 34-yr-old woman with idiopathic pulmonary artery hypertension who presented with nephrotic-range proteinuria. Kidney biopsy revealed enlarged glomeruli with mesangial-proliferative glomerulonephritis. A review of the pertinent literature and a discussion of the proposed pathophysiologic mechanisms leading to glomerulomegaly are presented.

Original languageEnglish (US)
Pages (from-to)1966-1970
Number of pages5
JournalJournal of the American Society of Nephrology
Volume8
Issue number12
StatePublished - Dec 1997

ASJC Scopus subject areas

  • Medicine(all)

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