TY - JOUR
T1 - Global Innervation Zone Identification with High-Density Surface Electromyography
AU - Zhang, Chuan
AU - Dias, Nicholas
AU - He, Jinbao
AU - Zhou, Ping
AU - Li, Sheng
AU - Zhang, Yingchun
PY - 2020/3
Y1 - 2020/3
N2 - Objective: The aim of this study is to compare the performance of three strategies in determining the global innervation zone (IZ) distribution. Methods: High-density surface electromyography was recorded from the biceps brachii muscle of seven healthy subjects under isometric voluntary contractions at 20%, 50%, and 100% of the maximal voluntary contraction and supramaximal musculocutaneous nerve stimulations. IZs were detected: first, by visual identification in a column-specific manner (IZ-1D); second, based on decomposed bipolar mapping of motor unit action potentials (IZ-2D); and third, by source imaging in the three-dimensional muscle space (IZ-3D). Results: All three IZ detection approaches have exhibited excellent trial-to-trial repeatability. Consistent IZ results were found in the axial direction of the arm across all three approaches, yet a difference was observed in the mediolateral direction. Conclusions: Among all three approaches, IZ-3D is capable of providing the most comprehensive information regarding the global IZ distribution, while maintaining high consistency with IZ-1D and IZ-2D results. Significance: IZ-3D approach can be a potential tool for global IZ imaging, which is critical to the clinical diagnosis and treatment of neuromuscular disorders.
AB - Objective: The aim of this study is to compare the performance of three strategies in determining the global innervation zone (IZ) distribution. Methods: High-density surface electromyography was recorded from the biceps brachii muscle of seven healthy subjects under isometric voluntary contractions at 20%, 50%, and 100% of the maximal voluntary contraction and supramaximal musculocutaneous nerve stimulations. IZs were detected: first, by visual identification in a column-specific manner (IZ-1D); second, based on decomposed bipolar mapping of motor unit action potentials (IZ-2D); and third, by source imaging in the three-dimensional muscle space (IZ-3D). Results: All three IZ detection approaches have exhibited excellent trial-to-trial repeatability. Consistent IZ results were found in the axial direction of the arm across all three approaches, yet a difference was observed in the mediolateral direction. Conclusions: Among all three approaches, IZ-3D is capable of providing the most comprehensive information regarding the global IZ distribution, while maintaining high consistency with IZ-1D and IZ-2D results. Significance: IZ-3D approach can be a potential tool for global IZ imaging, which is critical to the clinical diagnosis and treatment of neuromuscular disorders.
KW - Functional imaging
KW - innervation zone
KW - inverse methods
KW - muscle
KW - surface electromyography
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U2 - 10.1109/TBME.2019.2919906
DO - 10.1109/TBME.2019.2919906
M3 - Article
C2 - 31150334
AN - SCOPUS:85080078658
VL - 67
SP - 718
EP - 725
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
SN - 0018-9294
IS - 3
M1 - 8726155
ER -