Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

R. Dwayne Lunsford; Nancy A. Jenkins; Christine A. Kozak; Li fang Liang; Collen M. Silan; Neal G. Copeland; Jurrien Dean

doi:10.1016/0888-7543(90)90465-7

Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

R. Dwayne Lunsford, Nancy A. Jenkins, Christine A. Kozak, Li fang Liang, Collen M. Silan, Neal G. Copeland, Jurrien Dean

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and ZP3), the zona pellucida facilitates early events in fertilization and protects the embryo during preimplantation development. Using DNA isolated from hamster-mouse somatic cell hybrids and from C57BL 6J × Mus spretus interspecific backcross progeny, Zp-2 was located on chromosome 7, 11.3 ± 3.2 cM distal to Tyr, and Zp-3 was located on chromosome 5, 9.2 ± 2.9 cM distal to Gus.

Original language	English (US)
Pages (from-to)	184-187
Number of pages	4
Journal	Genomics
Volume	6
Issue number	1
DOIs	https://doi.org/10.1016/0888-7543(90)90465-7
State	Published - Jan 1990

ASJC Scopus subject areas

Genetics

Access to Document

10.1016/0888-7543(90)90465-7

Cite this

@article{ad950fb5716649e387e37a5f8eafcacb,

title = "Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins",

abstract = "The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and ZP3), the zona pellucida facilitates early events in fertilization and protects the embryo during preimplantation development. Using DNA isolated from hamster-mouse somatic cell hybrids and from C57BL 6J × Mus spretus interspecific backcross progeny, Zp-2 was located on chromosome 7, 11.3 ± 3.2 cM distal to Tyr, and Zp-3 was located on chromosome 5, 9.2 ± 2.9 cM distal to Gus.",

author = "\{Dwayne Lunsford\}, R. and Jenkins, \{Nancy A.\} and Kozak, \{Christine A.\} and Liang, \{Li fang\} and Silan, \{Collen M.\} and Copeland, \{Neal G.\} and Jurrien Dean",

note = "Funding Information: We thank S. Tilghman for the Alb probe, R. Ganschow for the Gus probe, B. Kwon for the Tyr probe, and J. Silver for the F\&l probe. Critical reading of this manuscript by R. Simpson and J. Silver was greatly appreciated. This research was supported in part by the National Cancer Institute, DHHS, under Contract NOl-CO-74101 with BRI. The NCI-Frederick Cancer Research Facility is fully accredited by the American Association of Laboratory Animal Care.",

year = "1990",

month = jan,

doi = "10.1016/0888-7543(90)90465-7",

language = "English (US)",

volume = "6",

pages = "184--187",

journal = "Genomics",

issn = "0888-7543",

publisher = "Academic Press",

number = "1",

}

TY - JOUR

T1 - Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

AU - Dwayne Lunsford, R.

AU - Jenkins, Nancy A.

AU - Kozak, Christine A.

AU - Liang, Li fang

AU - Silan, Collen M.

AU - Copeland, Neal G.

AU - Dean, Jurrien

N1 - Funding Information: We thank S. Tilghman for the Alb probe, R. Ganschow for the Gus probe, B. Kwon for the Tyr probe, and J. Silver for the F&l probe. Critical reading of this manuscript by R. Simpson and J. Silver was greatly appreciated. This research was supported in part by the National Cancer Institute, DHHS, under Contract NOl-CO-74101 with BRI. The NCI-Frederick Cancer Research Facility is fully accredited by the American Association of Laboratory Animal Care.

PY - 1990/1

Y1 - 1990/1

N2 - The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and ZP3), the zona pellucida facilitates early events in fertilization and protects the embryo during preimplantation development. Using DNA isolated from hamster-mouse somatic cell hybrids and from C57BL 6J × Mus spretus interspecific backcross progeny, Zp-2 was located on chromosome 7, 11.3 ± 3.2 cM distal to Tyr, and Zp-3 was located on chromosome 5, 9.2 ± 2.9 cM distal to Gus.

AB - The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and ZP3), the zona pellucida facilitates early events in fertilization and protects the embryo during preimplantation development. Using DNA isolated from hamster-mouse somatic cell hybrids and from C57BL 6J × Mus spretus interspecific backcross progeny, Zp-2 was located on chromosome 7, 11.3 ± 3.2 cM distal to Tyr, and Zp-3 was located on chromosome 5, 9.2 ± 2.9 cM distal to Gus.

UR - https://www.scopus.com/pages/publications/0025301112

UR - https://www.scopus.com/inward/citedby.url?scp=0025301112&partnerID=8YFLogxK

U2 - 10.1016/0888-7543(90)90465-7

DO - 10.1016/0888-7543(90)90465-7

M3 - Article

C2 - 1968044

AN - SCOPUS:0025301112

SN - 0888-7543

VL - 6

SP - 184

EP - 187

JO - Genomics

JF - Genomics

IS - 1

ER -

Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this