Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management

Hanny Sawaf, Tariku T. Gudura, Sylvester Dorobisz, Dianne Sandy, Xiangling Wang, Shane A. Bobart

Research output: Contribution to journalReview articlepeer-review

Abstract

Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis.

Original languageEnglish (US)
Pages (from-to)1-15
Number of pages15
JournalInternational Journal of Nephrology and Renovascular Disease
Volume16
DOIs
StatePublished - 2023

Keywords

  • chronic kidney disease
  • cystic kidney disease
  • end stage kidney disease
  • genetics

ASJC Scopus subject areas

  • Nephrology

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