Abstract
Adoptively transferred T cells have shown activity in treating viral infections after hemopoietic transplantation and anti-tumor activity against some malignancies such as melanoma and lymphoma. Current research focuses on defining the optimum type of cell for transfer to improve persistence and genetically modifying infused T cells to augment function, overcome tumor evasion strategies and allow ablation should adverse effects occur.
Original language | English (US) |
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Pages (from-to) | S15-S20 |
Journal | Biology of Blood and Marrow Transplantation |
Volume | 17 |
Issue number | 1 SUPPL |
DOIs | |
State | Published - Jan 2011 |
Keywords
- Gene transfer
- Suicide genes
- T lymphocytes
ASJC Scopus subject areas
- Transplantation
- Hematology