Genetic engineering of T-cell receptors: TCR takes to titin

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

In this issue of Blood, Linette et al report a cautionary tale - a lethal off-target toxicity following T-cell receptor (TCR) optimization to enhance affinity against a tumor-associated antigen, MAGE-A3.

Original languageEnglish (US)
Pages (from-to)853-854
Number of pages2
JournalBlood
Volume122
Issue number6
DOIs
StatePublished - Aug 8 2013

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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