Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression: A new SREBP1-dependent mechanism

Medicine & Life Sciences

• Sterols 99%
• LDL Receptors 99%
• Macrophages 59%
• Cholesterol 36%
• Liver X Receptors 33%
• Oxysterols 26%
• Sterol Regulatory Element Binding Protein 1 16%
• oxidized low density lipoprotein 12%
• Hyperlipoproteinemia Type II 7%
• High Fat Diet 6%
• Lipoproteins 5%
• Atherosclerosis 4%
• Ligands 4%
• Lipids 4%
• Mutation 3%
• Animals 3%

Chemistry

• Low-Density Lipoprotein 100%
• Cholesterol 47%
• Oxysterol 30%
• Sterol 14%
• Liver X Receptor Agonist 12%
• Hypercholesterolemic 10%
• Oxidised LDL 10%
• Lipoprotein 7%
• Fat 6%
• Mutation 5%
• Protein 5%
• Lipid 4%
• Ligand 2%