Genetic and environmental variance of renal parenchymal thickness: A twin study

Research output: Contribution to journalArticle

David Laszlo Tarnoki, Adam Domonkos Tarnoki, Levente Littvay, Pal Bata, Viktor Berczi, Zsolt Garami, Kinga Karlinger

Aim: To estimate heritability and environmental effects on renal parenchymal thickness. Methods: In this twin study, renal parenchymal thickness of 98 Hungarian healthy adult twin pairs (68 monozygotic, 30 dizygotic) without kidney disease was measured bilaterally using renal ultrasound with Esaote MyLab 70X ultrasound machine with low-frequency curved transducers (1-8 MHz). Results: In both monozygotic and dizygotic group there were more women (76.5%). Mean right and left renal parenchymal thickness was 1.32 ± 0.33 cm and 1.62 ± 0.31 cm, respectively. Age-and sex-adjusted heritability of renal parenchymal thickness was 0.0% (95% confidence interval, 0.0 to 50.2%), shared and unshared environmental factor was 30.2% (4.1 to 55.9%) and 69.8% (45.8 to 89.5%), respectively. Conclusion: This study shows a negligible role of heritability and an important role of environmental effects in developing renal parenchymal thickness, emphasizing the importance of lifestyle for primary prevention.

Original languageEnglish
Pages (from-to)550-554
Number of pages5
JournalCroatian Medical Journal
Volume54
Issue number6
DOIs
StatePublished - Dec 1 2013

PMID: 24382849

PMCID: PMC3914463

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Genetic and environmental variance of renal parenchymal thickness : A twin study. / Tarnoki, David Laszlo; Tarnoki, Adam Domonkos; Littvay, Levente; Bata, Pal; Berczi, Viktor; Garami, Zsolt; Karlinger, Kinga.

In: Croatian Medical Journal, Vol. 54, No. 6, 01.12.2013, p. 550-554.

Research output: Contribution to journalArticle

Harvard

Tarnoki, DL, Tarnoki, AD, Littvay, L, Bata, P, Berczi, V, Garami, Z & Karlinger, K 2013, 'Genetic and environmental variance of renal parenchymal thickness: A twin study' Croatian Medical Journal, vol. 54, no. 6, pp. 550-554. https://doi.org/10.3325/cmj.2013.54.550

APA

Tarnoki, D. L., Tarnoki, A. D., Littvay, L., Bata, P., Berczi, V., Garami, Z., & Karlinger, K. (2013). Genetic and environmental variance of renal parenchymal thickness: A twin study. Croatian Medical Journal, 54(6), 550-554. https://doi.org/10.3325/cmj.2013.54.550

Vancouver

Tarnoki DL, Tarnoki AD, Littvay L, Bata P, Berczi V, Garami Z et al. Genetic and environmental variance of renal parenchymal thickness: A twin study. Croatian Medical Journal. 2013 Dec 1;54(6):550-554. https://doi.org/10.3325/cmj.2013.54.550

Author

Tarnoki, David Laszlo ; Tarnoki, Adam Domonkos ; Littvay, Levente ; Bata, Pal ; Berczi, Viktor ; Garami, Zsolt ; Karlinger, Kinga. / Genetic and environmental variance of renal parenchymal thickness : A twin study. In: Croatian Medical Journal. 2013 ; Vol. 54, No. 6. pp. 550-554.

BibTeX

@article{0464e372bf534c4f8be19d90ca78fe8f,
title = "Genetic and environmental variance of renal parenchymal thickness: A twin study",
abstract = "Aim: To estimate heritability and environmental effects on renal parenchymal thickness. Methods: In this twin study, renal parenchymal thickness of 98 Hungarian healthy adult twin pairs (68 monozygotic, 30 dizygotic) without kidney disease was measured bilaterally using renal ultrasound with Esaote MyLab 70X ultrasound machine with low-frequency curved transducers (1-8 MHz). Results: In both monozygotic and dizygotic group there were more women (76.5{\%}). Mean right and left renal parenchymal thickness was 1.32 ± 0.33 cm and 1.62 ± 0.31 cm, respectively. Age-and sex-adjusted heritability of renal parenchymal thickness was 0.0{\%} (95{\%} confidence interval, 0.0 to 50.2{\%}), shared and unshared environmental factor was 30.2{\%} (4.1 to 55.9{\%}) and 69.8{\%} (45.8 to 89.5{\%}), respectively. Conclusion: This study shows a negligible role of heritability and an important role of environmental effects in developing renal parenchymal thickness, emphasizing the importance of lifestyle for primary prevention.",
author = "Tarnoki, {David Laszlo} and Tarnoki, {Adam Domonkos} and Levente Littvay and Pal Bata and Viktor Berczi and Zsolt Garami and Kinga Karlinger",
year = "2013",
month = "12",
day = "1",
doi = "10.3325/cmj.2013.54.550",
language = "English",
volume = "54",
pages = "550--554",
journal = "Croatian Medical Journal",
issn = "0353-9504",
publisher = "Medicinska Naklada d.o.o",
number = "6",

}

RIS

TY - JOUR

T1 - Genetic and environmental variance of renal parenchymal thickness

T2 - Croatian Medical Journal

AU - Tarnoki, David Laszlo

AU - Tarnoki, Adam Domonkos

AU - Littvay, Levente

AU - Bata, Pal

AU - Berczi, Viktor

AU - Garami, Zsolt

AU - Karlinger, Kinga

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Aim: To estimate heritability and environmental effects on renal parenchymal thickness. Methods: In this twin study, renal parenchymal thickness of 98 Hungarian healthy adult twin pairs (68 monozygotic, 30 dizygotic) without kidney disease was measured bilaterally using renal ultrasound with Esaote MyLab 70X ultrasound machine with low-frequency curved transducers (1-8 MHz). Results: In both monozygotic and dizygotic group there were more women (76.5%). Mean right and left renal parenchymal thickness was 1.32 ± 0.33 cm and 1.62 ± 0.31 cm, respectively. Age-and sex-adjusted heritability of renal parenchymal thickness was 0.0% (95% confidence interval, 0.0 to 50.2%), shared and unshared environmental factor was 30.2% (4.1 to 55.9%) and 69.8% (45.8 to 89.5%), respectively. Conclusion: This study shows a negligible role of heritability and an important role of environmental effects in developing renal parenchymal thickness, emphasizing the importance of lifestyle for primary prevention.

AB - Aim: To estimate heritability and environmental effects on renal parenchymal thickness. Methods: In this twin study, renal parenchymal thickness of 98 Hungarian healthy adult twin pairs (68 monozygotic, 30 dizygotic) without kidney disease was measured bilaterally using renal ultrasound with Esaote MyLab 70X ultrasound machine with low-frequency curved transducers (1-8 MHz). Results: In both monozygotic and dizygotic group there were more women (76.5%). Mean right and left renal parenchymal thickness was 1.32 ± 0.33 cm and 1.62 ± 0.31 cm, respectively. Age-and sex-adjusted heritability of renal parenchymal thickness was 0.0% (95% confidence interval, 0.0 to 50.2%), shared and unshared environmental factor was 30.2% (4.1 to 55.9%) and 69.8% (45.8 to 89.5%), respectively. Conclusion: This study shows a negligible role of heritability and an important role of environmental effects in developing renal parenchymal thickness, emphasizing the importance of lifestyle for primary prevention.

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U2 - 10.3325/cmj.2013.54.550

DO - 10.3325/cmj.2013.54.550

M3 - Article

VL - 54

SP - 550

EP - 554

JO - Croatian Medical Journal

JF - Croatian Medical Journal

SN - 0353-9504

IS - 6

ER -

ID: 2318958