TY - JOUR
T1 - Gene Transfer into Human Hematopoietic Progenitor Cells
T2 - A Review of Current Clinical Protocols
AU - Brenner, Malcolm K.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - Recent reviews by Clay Smith (1992) in this journal and by W. French Anderson (1990) and A. Dusty Miller (1992) have described the technologies used for gene transfer, the potential applications of the approach, and the safety issues that require consideration. This review will have a narrower focus. It will deal specifically with current and forthcoming clinical protocols for gene transfer into hemopoietic progenitor cells, because a major goal of gene therapy for malignant and nonmalignant disease is to transfer and express genes on a long-term basis in these cells or their progeny.
AB - Recent reviews by Clay Smith (1992) in this journal and by W. French Anderson (1990) and A. Dusty Miller (1992) have described the technologies used for gene transfer, the potential applications of the approach, and the safety issues that require consideration. This review will have a narrower focus. It will deal specifically with current and forthcoming clinical protocols for gene transfer into hemopoietic progenitor cells, because a major goal of gene therapy for malignant and nonmalignant disease is to transfer and express genes on a long-term basis in these cells or their progeny.
UR - http://www.scopus.com/inward/record.url?scp=0027263269&partnerID=8YFLogxK
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U2 - 10.1089/scd.1.1993.2.7
DO - 10.1089/scd.1.1993.2.7
M3 - Article
C2 - 7522875
AN - SCOPUS:0027263269
SN - 1525-8165
VL - 2
SP - 7
EP - 17
JO - Journal of Hematotherapy and Stem Cell Research
JF - Journal of Hematotherapy and Stem Cell Research
IS - 1
ER -