Gene Transfer into Human Hematopoietic Progenitor Cells: A Review of Current Clinical Protocols

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Recent reviews by Clay Smith (1992) in this journal and by W. French Anderson (1990) and A. Dusty Miller (1992) have described the technologies used for gene transfer, the potential applications of the approach, and the safety issues that require consideration. This review will have a narrower focus. It will deal specifically with current and forthcoming clinical protocols for gene transfer into hemopoietic progenitor cells, because a major goal of gene therapy for malignant and nonmalignant disease is to transfer and express genes on a long-term basis in these cells or their progeny.

Original languageEnglish (US)
Pages (from-to)7-17
Number of pages11
JournalJournal of Hematotherapy and Stem Cell Research
Volume2
Issue number1
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Immunology
  • Hematology

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