Gene transfer in haematological malignancy

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Although gene transfer was first suggested to treat inherited monogenic disorders, at present most clinical protocols are intended to treat patients with malignant disease. Although current vector technologies profoundly limit the potential therapeutic applications of gene transfer, the technique is already being successfully used to complement longer established therapies. This article reviews current and forthcoming applications of gene transfer to treat haematological malignancies.

Original languageEnglish (US)
Pages (from-to)491-497
Number of pages7
JournalAnnals of Medicine
Volume28
Issue number6
DOIs
StatePublished - 1996

Keywords

  • Cytotoxic T cells
  • Gene therapy
  • Haematological malignancies
  • Haematopoietic stem cells
  • Vectors

ASJC Scopus subject areas

  • Medicine(all)

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