G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients

H. Deng; Weidong Le; X. Zhang; T. H. Pan; J. Jankovic

doi:10.1111/j.1600-0404.2005.00383.x

G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients

H. Deng, Weidong Le, X. Zhang, T. H. Pan, J. Jankovic

Houston Methodist

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Objective - To determine whether the G309D and W437OPA mutations in PINK1 gene are present in American Caucasian population of patients with Parkinson's disease (PD). Methods - We searched for the G309D and W437OPA mutation by sequencing the regions of interest in the PINK1 gene in 237 unrelated Caucasian patients. Results - None of the 237 samples showed the G309D or W437OPA mutations. Conclusions - The G309D and W437OPA mutations in PINK1 gene probably do not represent common causes of familial or sporadic PD in a Caucasian population.

Original language	English (US)
Pages (from-to)	351-352
Number of pages	2
Journal	Acta Neurologica Scandinavica
Volume	111
Issue number	6
DOIs	https://doi.org/10.1111/j.1600-0404.2005.00383.x
State	Published - Jun 2005

Keywords

Caucasian
G309D
Parkinson's disease
PINK1
W4370PA

ASJC Scopus subject areas

Clinical Neurology
General Neuroscience

Access to Document

10.1111/j.1600-0404.2005.00383.x

Cite this

@article{a0eb5597cbe64b12a4807df136c8dc55,

title = "G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients",

abstract = "Objective - To determine whether the G309D and W437OPA mutations in PINK1 gene are present in American Caucasian population of patients with Parkinson's disease (PD). Methods - We searched for the G309D and W437OPA mutation by sequencing the regions of interest in the PINK1 gene in 237 unrelated Caucasian patients. Results - None of the 237 samples showed the G309D or W437OPA mutations. Conclusions - The G309D and W437OPA mutations in PINK1 gene probably do not represent common causes of familial or sporadic PD in a Caucasian population.",

keywords = "Caucasian, G309D, Parkinson's disease, PINK1, W4370PA",

author = "H. Deng and Weidong Le and X. Zhang and Pan, \{T. H.\} and J. Jankovic",

year = "2005",

month = jun,

doi = "10.1111/j.1600-0404.2005.00383.x",

language = "English (US)",

volume = "111",

pages = "351--352",

journal = "Acta Neurologica Scandinavica",

issn = "0001-6314",

publisher = "Wiley",

number = "6",

}

TY - JOUR

T1 - G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients

AU - Deng, H.

AU - Le, Weidong

AU - Zhang, X.

AU - Pan, T. H.

AU - Jankovic, J.

PY - 2005/6

Y1 - 2005/6

N2 - Objective - To determine whether the G309D and W437OPA mutations in PINK1 gene are present in American Caucasian population of patients with Parkinson's disease (PD). Methods - We searched for the G309D and W437OPA mutation by sequencing the regions of interest in the PINK1 gene in 237 unrelated Caucasian patients. Results - None of the 237 samples showed the G309D or W437OPA mutations. Conclusions - The G309D and W437OPA mutations in PINK1 gene probably do not represent common causes of familial or sporadic PD in a Caucasian population.

AB - Objective - To determine whether the G309D and W437OPA mutations in PINK1 gene are present in American Caucasian population of patients with Parkinson's disease (PD). Methods - We searched for the G309D and W437OPA mutation by sequencing the regions of interest in the PINK1 gene in 237 unrelated Caucasian patients. Results - None of the 237 samples showed the G309D or W437OPA mutations. Conclusions - The G309D and W437OPA mutations in PINK1 gene probably do not represent common causes of familial or sporadic PD in a Caucasian population.

KW - Caucasian

KW - G309D

KW - Parkinson's disease

KW - PINK1

KW - W4370PA

UR - https://www.scopus.com/pages/publications/18944385686

UR - https://www.scopus.com/inward/citedby.url?scp=18944385686&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0404.2005.00383.x

DO - 10.1111/j.1600-0404.2005.00383.x

M3 - Article

C2 - 15876334

AN - SCOPUS:18944385686

SN - 0001-6314

VL - 111

SP - 351

EP - 352

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

IS - 6

ER -

G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this