G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients

H. Deng, Weidong Le, X. Zhang, T. H. Pan, J. Jankovic

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Objective - To determine whether the G309D and W437OPA mutations in PINK1 gene are present in American Caucasian population of patients with Parkinson's disease (PD). Methods - We searched for the G309D and W437OPA mutation by sequencing the regions of interest in the PINK1 gene in 237 unrelated Caucasian patients. Results - None of the 237 samples showed the G309D or W437OPA mutations. Conclusions - The G309D and W437OPA mutations in PINK1 gene probably do not represent common causes of familial or sporadic PD in a Caucasian population.

Original languageEnglish (US)
Pages (from-to)351-352
Number of pages2
JournalActa Neurologica Scandinavica
Volume111
Issue number6
DOIs
StatePublished - Jun 2005

Keywords

  • Caucasian
  • G309D
  • Parkinson's disease
  • PINK1
  • W4370PA

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'G309D and W437OPA PINK1 mutations in Caucasian Parkinson's disease patients'. Together they form a unique fingerprint.

Cite this