Future Outlook of Nanopharmacy: Challenges and Opportunities

The use of nanocarriers (NCs) for the delivery of drugs, termed as Nanopharmacy, has emerged as a novel field in medicine integrating nanoscale technologies with materials sciences, chemistry, pharmacy, and biology. This chapter discusses several explanations for why NCs as anticancer drugs do not fulfill their full potential. Animal studies are essential preclinical models in the field of anticancer drugs development in order to measure the performance of the NCs and the encapsulated drug under whole animal conditions. It is more than necessary to develop reliable techniques that allow an accurate determination of NC stability in biological fluids along with an in vivo like blood medium. Among the important parameters are size distribution, surface charge, quantitative analysis of lipids composition, drug loading rate, and formulation stability. Moving from drug entrapped in NCs at a lab scale to scale up production for clinical testing is a multilevel complex problem, which requires optimization steps or various parameters.