Fungal-bacterial interactions and their relevance in health

Marios Arvanitis, Eleftherios Mylonakis

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations

Abstract

Cross-kingdom interactions between bacteria and fungi are a common occurrence in the environment. Recent studies have identified various types of interactions that either can take the form of a synergistic relationship or can result in an antagonistic interplay with the subsequent destruction or inhibition of growth of bacteria, fungi or both. This cross-kingdom communication is of particular significance in human health and disease, as bacteria and fungi commonly colonize various human surfaces and their interactions can at times alter the outcome of invasive infections. Moreover, mixed infections from both bacteria and fungi are relatively common among critically ill patients and individuals with weak immune responses. The purpose of this review is to summarize our knowledge on the type of interactions between bacteria and fungi and their relevance in human infections.

Original languageEnglish (US)
Pages (from-to)1442-1446
Number of pages5
JournalCellular Microbiology
Volume17
Issue number10
DOIs
StatePublished - Oct 1 2015

Keywords

  • Bacteria
  • Caenorrhabditis elegans
  • Candidiasis
  • Fungi
  • Interactions
  • Pneumonia
  • VAP

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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