TY - GEN
T1 - Functional validation of an implantable medical dosing device by MRI at 3T
AU - Anderson, Jeff R.
AU - Ferrati, Silvia
AU - Karmonik, Chistof
AU - Grattoni, Alessandro
N1 - Publisher Copyright:
© 2014 IEEE.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2014/11/2
Y1 - 2014/11/2
N2 - Sustained release of a small molecule from a prototype implantable drug delivery device was monitored via MRI in an ex vivo tissue phantom over a period of two days. T1 mapping was used as a method to quantify analyte concentration. Continuous, controlled release was observed. The MRI methodology was thus found to be appropriate for device validation and quality assurance/control.
AB - Sustained release of a small molecule from a prototype implantable drug delivery device was monitored via MRI in an ex vivo tissue phantom over a period of two days. T1 mapping was used as a method to quantify analyte concentration. Continuous, controlled release was observed. The MRI methodology was thus found to be appropriate for device validation and quality assurance/control.
UR - http://www.scopus.com/inward/record.url?scp=84929494002&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929494002&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2014.6944091
DO - 10.1109/EMBC.2014.6944091
M3 - Conference contribution
C2 - 25570459
AN - SCOPUS:84929494002
T3 - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
SP - 2346
EP - 2347
BT - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Y2 - 26 August 2014 through 30 August 2014
ER -