TY - JOUR
T1 - Functional morphology analysis of the left anterior descending coronary artery in EBCT images
AU - Kakadiaris, Ioannis A.
AU - Santamaría-Pang, Alberto
AU - Pednekar, Amol
N1 - Funding Information:
Manuscript received August 11, 2008; revised January 23, 2009, August 5, 2009, September 1, 2009, and October 19, 2009; accepted October 25, 2009. Date of publication February 18, 2010; date of current version July 14, 2010. This work was supported in part by the National Science Foundation under Grant IIS–0431144, Grant IIS–0335578, and Grant IIS–9985482. The work of A. Santamaría-Pang was performed while the author was with the Computational Biomedicine Laboratory. The work of A. Pednekar was performed while the author was with the Computational Biomedicine Laboratory. Asterisk indicates corresponding author.
PY - 2010/8
Y1 - 2010/8
N2 - In this paper, we present a physics-based deformable model framework for morphological and motion analysis of the left anterior descending (LAD) coronary artery. The proposed model is designed to capture the complex motion that the LAD undergoes during the cardiac cycle. The key idea is to define a local coordinate system for the heart and to parameterize both the shape and motion of the LAD in a single framework. The shape of the LAD is modeled as a parametric generalized cylinder, and the motion during the heart cycle is modeled as a composite of three components, which are as follows: 1) longitudinal deformation, 2) radial displacement, and 3) angular displacement over the cardiac cycle. The proposed framework for the LAD shapemotion estimation is generic, since it does not assume any particular tubular shape. Results obtained for four human subjects using electron beam computed tomography data are in agreement with LAD shapemotion deformations reported in the literature.
AB - In this paper, we present a physics-based deformable model framework for morphological and motion analysis of the left anterior descending (LAD) coronary artery. The proposed model is designed to capture the complex motion that the LAD undergoes during the cardiac cycle. The key idea is to define a local coordinate system for the heart and to parameterize both the shape and motion of the LAD in a single framework. The shape of the LAD is modeled as a parametric generalized cylinder, and the motion during the heart cycle is modeled as a composite of three components, which are as follows: 1) longitudinal deformation, 2) radial displacement, and 3) angular displacement over the cardiac cycle. The proposed framework for the LAD shapemotion estimation is generic, since it does not assume any particular tubular shape. Results obtained for four human subjects using electron beam computed tomography data are in agreement with LAD shapemotion deformations reported in the literature.
KW - Deformable model-based tracking
KW - functional morphology analysis
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U2 - 10.1109/TBME.2010.2043254
DO - 10.1109/TBME.2010.2043254
M3 - Article
C2 - 20176530
AN - SCOPUS:77954640251
SN - 0018-9294
VL - 57
SP - 1886
EP - 1896
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 8
M1 - 5416295
ER -