Functional Magnetic Resonance Imaging in the Neuromodulation of Pain

Ernest J. Barthélemy, Jonathan J. Rasouli, Kurt A. Yaeger, Brian H. Kopell

Research output: Chapter in Book/Report/Conference proceedingChapter


Physical pain is a leading cause of healthcare spending, work-related disability, and morbidity in the United States. The development of advanced functional magnetic resonance imaging (MRI) techniques such as blood oxygenation level dependent imaging, arterial spin labeling, and resting-state functional connectivity MRI offers researchers the prospect of developing objective diagnostic instruments for pain syndromes. This chapter reviews recent advancements in functional imaging, and the diagnostic and therapeutic opportunities they present in pain management.

Original languageEnglish (US)
Title of host publicationNeuromodulation
Subtitle of host publicationComprehensive Textbook of Principles, Technologies, and Therapies, Second Edition: Volume 1-3
Number of pages11
ISBN (Electronic)9780128053539
ISBN (Print)9780128093023
StatePublished - Jan 1 2018


  • BOLD
  • Chronic pain
  • fMRI
  • Functional MRI
  • MRI
  • Spinal cord stimulation

ASJC Scopus subject areas

  • Neuroscience(all)


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