Functional dyspepsia: The role of visceral hypersensitivity in its pathogenesis

John Keohane, Eamonn M.M. Quigley

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Functional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD.

Original languageEnglish (US)
Pages (from-to)2672-2676
Number of pages5
JournalWorld Journal of Gastroenterology
Volume12
Issue number17
DOIs
StatePublished - May 7 2006

Keywords

  • Helicobacter pylori
  • Motor dysfunction
  • Psychosocial
  • Visceral hypersensitivity

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Functional dyspepsia: The role of visceral hypersensitivity in its pathogenesis'. Together they form a unique fingerprint.

Cite this