Functional dyspepsia and nonerosive reflux disease: Clinical interactions and their implications

John Keohane, Eamonn Martin Quigley

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Functional dyspepsia or nonulcer dyspepsia, and nonerosive reflux disease (NERD) or endoscopy-negative reflux disease, are common reasons for referral to a gastroenterologist. Although there is much confusion with regard to definition, recent research would suggest that these 2 conditions are linked and may represent components in the spectrum of the same disease entity, in terms of both symptoms and pathophysiology. Several theories have been proposed regarding the etiology of these disorders, including acid exposure, visceral hypersensitivity, impaired fundal accommodation, delayed gastric emptying, and Helicobacter pylori infection.

Original languageEnglish (US)
Article number31
JournalMedGenMed Medscape General Medicine
Volume9
Issue number3
StatePublished - Aug 20 2007

ASJC Scopus subject areas

  • Medicine(all)

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